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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >A survey on staging and treatment in uterine cervical carcinoma in the Radiotherapy Cooperative Group of the European Organization for Research and Treatment of Cancer.
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A survey on staging and treatment in uterine cervical carcinoma in the Radiotherapy Cooperative Group of the European Organization for Research and Treatment of Cancer.

机译：欧洲癌症研究与治疗组织放射治疗合作小组对子宫颈癌分期和治疗的调查。

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BACKGROUND: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the European Organization for Research and Treatment of Cancer (EORTC), we conducted a survey in 1997-1998 to determine the variability of pre-treatment assessment and treatment options. The variability of choosing surgery, defined radiation therapy techniques and chemotherapy are investigated, as well as the center's choices of future treatment strategies. METHODS: Fifty two of 81 RCG centers from the RCG have participated in the survey. As one would expect, there is a large variation in the techniques used for pretreatment evaluation and treatment options. There is no 'standard' for reporting acute and late side effects. Chemotherapy is used neither systematically nor uniformly, and some centers continue to use neadjuvant chemotherapy modalities. RESULTS: Furthermore, the survey reveals that there is a strong demand for the reduction of overall treatment-time, for clinical investigation of novel combined modality treatment strategies, especially chemo-radiation therapy, and also for the use of new radiation sensitizers. CONCLUSION: We conclude that a more homogeneous approach to the pretreatment evaluation as well as treatment techniques is required in order to allow adequate quality control in any future trial of the RCG in the EORTC.
机译：背景：晚期宫颈癌的治疗效果仍然不理想。为了在欧洲癌症研究与治疗组织（EORTC）的放射治疗合作小组（RCG）中详细研究一项新的试验，我们在1997-1998年进行了一项调查，以确定治疗前评估和治疗选择的变异性。研究了选择手术，确定的放射治疗技术和化学疗法的可变性，以及中心对未来治疗策略的选择。方法：来自RCG的81个RCG中心中有52个参与了调查。正如人们所期望的，用于预处理评估和治疗选择的技术存在很大差异。没有报告急性和晚期副作用的“标准”。既没有系统地也没有统一地使用化学疗法，并且一些中心继续使用辅助化学疗法。结果：此外，调查显示，对于减少整体治疗时间，对新型联合治疗策略（尤其是化学放射疗法）的临床研究以及使用新型放射增敏剂的需求，都存在强烈的需求。结论：我们得出结论，为了在EORTC的RCG的任何未来试验中能够进行适当的质量控制，需要一种更加均质的方法进行预处理评估和处理技术。

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