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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Risk factors for voice quality after radiotherapy for early glottic cancer.
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Risk factors for voice quality after radiotherapy for early glottic cancer.

机译：早期声门癌放疗后语音质量的危险因素。

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摘要

BACKGROUND AND PURPOSE: In the majority of patients irradiated for early glottic cancer an abnormal voice was reported. The purpose of the study was to determine the factors influencing voice quality after radiotherapy for T1 glottic cancer. METHODS: The voices of 75 male patients irradiated for T1 glottic carcinoma were assessed subjectively and objectively by acoustic analyses and aerodynamic measurements. The laryngeal function and morphology were evaluated by videolaryngostroboscopy. The data on smoking habits, the associated diseases influencing voice quality, the extent of the tumor, the type of biopsy, and the irradiation technique were collected from the medical records. The data on the factors influencing voice quality were compared for patients with a normalear-normal voice and those with a hoarse voice. RESULTS: Voice quality was at least slightly abnormal in 94.7% and 81.3% of patients, when assessed perceptively and objectively, respectively. Smoking after the completed treatment, more severe morphologic alterations of the vocal folds, dryness of the throat, incomplete closure of the vocal folds and functional voice disorders expressed as supraglottic activity adversely influenced the voice quality. A good correlation between the perceptive voice assessment and the acoustic analyses was established. CONCLUSIONS: After the successful irradiation for T1 glottic carcinoma, the great majority of the patients have at least a slightly hoarse voice. A better voice outcome could be achieved if radiotherapy was followed by the patient's cessation of smoking and the appropriate voice therapy.
机译：背景与目的：在接受早期声门癌照射的大多数患者中，都报告了声音异常。该研究的目的是确定影响T1声门癌放疗后语音质量的因素。方法：通过声学分析和空气动力学测量，主观和客观地评估了75例男性T1声门癌患者的声音。通过视频喉镜检查评估喉功能和形态。从病历中收集了吸烟习惯，影响语音质量的相关疾病，肿瘤范围，活检类型和放射技术的数据。比较了正常/接近正常的声音和声音嘶哑的患者的影响语音质量的因素数据。结果：分别进行感知和客观评估时，分别有94.7％和81.3％的患者的语音质量至少略有异常。完成治疗后吸烟，声带的形态变化更为严重，喉咙干燥，声带闭合不完全以及声门上活动表现为功能性语音障碍，对语音质量产生不利影响。在感知语音评估和声学分析之间建立了良好的相关性。结论：成功地放射治疗了T1声门癌后，绝大多数患者的声音至少有些沙哑。如果放疗后患者戒烟并进行适当的声音疗法，则可以取得更好的声音效果。

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