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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Molecular radiation biology: perspectives for radiation oncology.
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Molecular radiation biology: perspectives for radiation oncology.

机译：分子放射生物学：放射肿瘤学的观点。

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摘要

Molecular radiation biology has become a powerful discipline and tool for detailed investigations into biological mechanisms of problems and aspects of modern radiation oncology. In this context special emphasis is given to the mechanisms of DNA-repair and their relevance for radiation therapy, to the relevance of radiation-induced signal transduction for normal and tumour cell response, to the role of the micro-environment for the modification of tumour as well as normal tissue responses to radiation, and last but not the least to the aspects of individualization and molecular targeting in radiation therapy. These topics were extensively discussed during the 11 th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, which was held at the Wolfsberg Conference Center in Ermatingen, Switzerland, from June 27 to 29, 2009. About 160 basic, preclinical and clinical scientists from 21 countries worldwide participated in this 2009-edition of the Wolfsberg Meeting Series on Molecular Radiation Biology/Oncology to discuss cutting-edge research in the above-mentioned topics. In the following some of the major achievements, which have been made over the recent years in the fields of basic and clinically oriented research in radiation biology as well as experimental and translational radiation oncology will be reviewed.
机译：分子放射生物学已成为对问题的生物学机制和现代放射肿瘤学方面进行详细研究的强大学科和工具。在这种情况下，特别强调DNA修复的机制及其与放射治疗的相关性，与放射诱导的信号转导对正常和肿瘤细胞反应的相关性，微环境在肿瘤修饰中的作用以及正常组织对放射线的反应，最后但并非最不重要的一点是放射线疗法中的个体化和分子靶向方面。这些主题在2009年6月27日至29日在瑞士Ermatingen的Wolfsberg会议中心举行的第11届国际Wolfsberg分子辐射生物学/肿瘤学国际会议上进行了广泛讨论。约有160位来自21岁的基础，临床前和临床科学家世界各国参加了2009年沃尔夫斯堡分子辐射生物学/肿瘤学会议系列的讨论，以讨论上述主题的前沿研究。接下来，将回顾近年来在放射生物学以及实验和转化放射肿瘤学的基础和临床导向研究领域中取得的一些主要成就。

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