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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Geographical distribution of lymph node metastases on MR lymphography in prostate cancer patients
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Geographical distribution of lymph node metastases on MR lymphography in prostate cancer patients

机译:前列腺癌患者MR淋巴结的淋巴结转移的地理分布

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Purpose: To investigate the pattern of lymph node spread on magnetic resonance lymphography (MRL) in prostate cancer patients and compare this pattern to the clinical target volume for elective pelvis irradiation as defined by the radiation therapy oncology group (RTOG-CTV). Methods and materials: The charts of 60 intermediate and high risk prostate cancer patients with non-enlarged positive lymph nodes on MRL were reviewed. Positive lymph nodes were assigned to a lymph node region according to the guidelines for delineation of the RTOG-CTV. Five lymph node regions outside this RTOG-CTV were defined: the para-aortal, proximal common iliac, pararectal, paravesical and inguinal region. Results: Fifty-three percent of the patients had an MRL-positive lymph node in a lymph node region outside the RTOG-CTV. The most frequently involved aberrant sites were the proximal common iliac, the pararectal and para-aortal region, which were affected in 30%, 25% and 18% respectively. Conclusion: More than half of the patients had an MRL-positive lymph node outside the RTOG-CTV. To reduce geographical miss while minimizing the toxicity of radiotherapy, image based definition of an individual target volume seems to be necessary. ? 2013 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology.
机译:目的:研究前列腺癌患者在磁共振淋巴造影(MRL)上的淋巴结扩散模式,并将其与放射治疗肿瘤学组(RTOG-CTV)定义的选择性骨盆照射的临床目标体积进行比较。方法和材料:回顾了60例MRL未加长阳性淋巴结的中,高危前列腺癌患者的病历。根据RTOG-CTV的划分指南,将阳性淋巴结分配至淋巴结区域。定义了该RTOG-CTV之外的五个淋巴结区域:主动脉旁,common总近,直肠旁,膀胱旁和腹股沟区域。结果:53%的患者在RTOG-CTV以外的淋巴结区域有MRL阳性淋巴结。最常见的异常部位是common总近端,直肠旁和主动脉旁区域,分别受累的比例为30%,25%和18%。结论:超过一半的患者在RTOG-CTV之外具有MRL阳性淋巴结。为了减少地理遗漏,同时最大程度地降低放射治疗的毒性,似乎有必要基于图像确定单个目标体积。 ? 2013 Elsevier Ireland Ltd.保留所有权利。放射疗法和肿瘤学。

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