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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Mammary fat necrosis following radiotherapy in the conservative management of localized breast cancer: does it matter?
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Mammary fat necrosis following radiotherapy in the conservative management of localized breast cancer: does it matter?

机译:在局部乳腺癌的保守治疗中放疗后的乳腺脂肪坏死:重要吗?

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PURPOSE: Fat necrosis is a well-described and relatively common complication arising from post-lumpectomy irradiation of the breast, most commonly breast brachytherapy. We wish to assess the clinical significance of fat necrosis resulting from post-lumpectomy breast irradiation. METHODS: We reviewed the literature to determine the overall incidence and significance of fat necrosis to determine whether or not fat necrosis poses a significant clinical problem. RESULTS: Fat necrosis occurs in up to one-quarter of patients following post-lumpectomy breast irradiation. Only rarely is invasive intervention required however, it does significantly degrade the quality of all modalities of breast imaging. CONCLUSIONS: Fat necrosis is a common complication of radiotherapy which rarely requires therapeutic intervention. However, post-therapeutic clinical imaging such as mammography, ultrasound and magnetic resonance imaging are affected which may result in additional diagnostic procedures up to and including biopsy.
机译:目的:脂肪坏死是乳房肿块切除术后放疗(最常见的是乳房近距离放疗)引起的一种描述良好且相对常见的并发症。我们希望评估肿块切除术后乳房照射导致的脂肪坏死的临床意义。方法:我们回顾了文献以确定脂肪坏死的总体发生率和意义,以确定脂肪坏死是否构成重大的临床问题。结果:脂肪切除术后乳房切除术后多达四分之一的患者发生脂肪坏死。很少需要侵入性干预,但是,它确实会显着降低乳房成像所有形式的质量。结论:脂肪坏死是放疗的常见并发症,很少需要治疗干预。但是,治疗后的临床成像(如乳房X线照片,超声和磁共振成像)会受到影响,这可能会导致额外的诊断程序,包括活检。

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