Histopathological effects of preoperative chemoradiotherapy for pancreatic cancer: An analysis for the impact of radiation and gemcitabine doses

Hirata Takero; Teshima Teruki; Nishiyama Kinji; Ogawa Kazuhiko; Otani Keisuke; Kawaguchi Yoshifumi; Konishi Koji; Tomita Yasuhiko; Takahashi Hidenori; Ohigashi Hiroaki; Ishikawa Osamu

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Histopathological effects of preoperative chemoradiotherapy for pancreatic cancer: An analysis for the impact of radiation and gemcitabine doses

机译：胰腺癌术前放化疗的组织病理学影响：放射和吉西他滨剂量的影响分析

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Background and purpose: Histopathological findings of patients who underwent resection for pancreatic adenocarcinoma (PC) after preoperative chemoradiotherapy (CRT) reportedly showed beneficial effects. The purpose of our study was to evaluate the correlation between histopathological effects (HE) of preoperative CRT and treatment parameters [radiation and gemcitabine (GEM) doses].

机译：背景与目的：据报道，术前放化疗（CRT）后行胰腺腺癌（PC）切除术的患者的组织病理学发现显示出有益的效果。我们研究的目的是评估术前CRT的组织病理学效应（HE）与治疗参数[放射和吉西他滨（GEM）剂量]之间的相关性。

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《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2015年第1期|共6页
作者
Hirata Takero; Teshima Teruki; Nishiyama Kinji; Ogawa Kazuhiko; Otani Keisuke; Kawaguchi Yoshifumi; Konishi Koji; Tomita Yasuhiko; Takahashi Hidenori; Ohigashi Hiroaki; Ishikawa Osamu;
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正文语种 eng
中图分类肿瘤学;
关键词
Pancreatic cancer; Preoperative chemoradiotherapy; Gemcitabine; Histopathological effects;

机译：胰腺癌;术前放化疗;吉西他滨;组织病理学影响;

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1. Histopathological effects of preoperative chemoradiotherapy for pancreatic cancer: An analysis for the impact of radiation and gemcitabine doses [J] . Hirata Takero, Teshima Teruki, Nishiyama Kinji, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2015,第1期

机译：胰腺癌术前放化疗的组织病理学影响：放射和吉西他滨剂量的影响分析
2. Pathological and clinical impact of neoadjuvant chemoradiotherapy using full-dose gemcitabine and concurrent radiation for resectable pancreatic cancer. [J] . Masayuki Sho, Takahiro Akahori, Toshihiro Tanaka, Journal of hepato-biliary-pancreatic sciences . 2013,第2期

机译：Neoadjuvant ChemoRAdiotaupy使用全剂量吉西他滨的病理和临床影响，并进行可重新切除胰腺癌的同步辐射。
3. R0 Resection for Locally Advanced Pancreatic Cancer with Low-dose Gemcitabine with Wide Irradiation Area as Neoadjuvant Chemoradiotherapy [J] . HIROFUMI KAMACHI, YOUSUKE TSURUGA, TATSUYA ORIMO, In vivo. . 2018,第5期

机译：低剂量吉西他滨照射范围广的局部晚期胰腺癌的R0切除作为新辅助放化疗
4. Analysis of gene expression in gemcitabine resistant cells derived from human pancreatic cancer cell [C] . Zhang Shaoxuan, Furugawa Tatsuhiko, Takahashi Homare, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：人胰腺癌细胞来源的吉西他滨耐药细胞基因表达分析
5. Pharmacokinetic and Pharmacodynamic Analysis of Gemcitabine and Birinapant Combinations in Pancreatic Cancer. [D] . Zhu, Xu. 2017

机译：吉西他滨和Birinapant组合在胰腺癌中的药代动力学和药效学分析。
6. R0 Resection for Locally Advanced Pancreatic Cancer with Low-dose Gemcitabine with Wide Irradiation Area as Neoadjuvant Chemoradiotherapy [O] . HIROFUMI KAMACHI, YOUSUKE TSURUGA, TATSUYA ORIMO, 2018

机译：小剂量吉西他滨照射范围广的局部晚期胰腺癌的R0切除作为新辅助放化疗
7. A Multi-Institutional Phase II Trial of Preoperative Full-Dose Gemcitabine and Concurrent Radiation for Patients With Potentially Resectable Pancreatic Carcinoma [O] . Timothy J. Kinsella, Philip A. Philip, Cornelius J. Mcginn 2014

机译：可行性切除胰腺癌患者术前全剂量吉西他滨和同时放射的多机构II期试验

Histopathological effects of preoperative chemoradiotherapy for pancreatic cancer: An analysis for the impact of radiation and gemcitabine doses

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