Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development

MaliR.S.; KapurR.

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Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development

机译：IS PI3激酶调节亚基在肥大细胞发育中的独特和冗余作用

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Mast cells are effector cells of the immune system that are derived from hemato-poietic stem cells. These cells regulate both innate and adaptive immunity and have also been implicated in a variety of inflammatory diseases. The maturation of these cells is dependent on signals regulated via the c-Kit and IL-3 receptors as well as transcription factors including MITF While the role of c-Kit and IL-3 receptor in mast development is known; the signaling molecules downstream from these receptors involved in regulating the growth and maturation of these cells are poorly understood.

机译：肥大细胞是免疫系统的效应细胞，其源自造血干细胞。这些细胞调节先天免疫和适应性免疫，还与多种炎性疾病有关。这些细胞的成熟取决于通过c-Kit和IL-3受体以及包括MITF在内的转录因子调控的信号。这些受体下游参与调节这些细胞的生长和成熟的信号分子了解得很少。

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《Cell cycle》 |2013年第1期|共2页
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MaliR.S.; KapurR.;
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正文语种 eng
中图分类细胞生物学;
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1. Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development [J] . MaliR.S., KapurR. Cell cycle . 2013,第1期

机译：IS PI3激酶调节亚基在肥大细胞发育中的独特和冗余作用
2. Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class IA Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation [J] . Peilin Ma, Sasidhar Vemula, Veerendra Munugalavadla, Molecular and Cellular Biology . 2011,第19期

机译：Lyn，IA类磷脂酰肌醇3-激酶的p85α调节亚基与SHIP之间的平衡相互作用对于肥大细胞生长和成熟至关重要
3. Unique and redundant beta-catenin regulatory roles of two Dishevelled paralogs during C. elegans asymmetric cell division [J] . Baldwin Austin T., Clemons Amy M., Phillips Bryan T. Journal of Cell Science . 2016,第5期

机译：秀丽隐杆线虫不对称细胞分裂过程中两个杂乱旁系同源物的独特和冗余β-catenin调节作用
4. Role of CC chemokines and their receptors in multiple aspects of mast cell biology: comparative protein profiling of FcepsilonRI- and/or CCR1-engaged mast cells using protein chip technology [C] . Masako Toda, Takao Nakamura, Masaharu Ohbayashi, Symposium on Mast Cells and Basophils: Development, Activation and Roles in Allergic/Autoimmune Disease . 2005

机译：CC趋化因子及其受体在肥大细胞生物学多个方面的作用：使用蛋白质芯片技术的Fcepsilonri-and-/或CCR1接合肥大细胞的比较蛋白质分析
5. Role of the class I(A) phosphoinositide 3-kinase regulatory subunit p85 in metabolism, development and cancer. [D] . Luo, Ji. 2006

机译：I（A）类磷酸肌醇3激酶调节亚基p85在代谢，发育和癌症中的作用。
6. Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development [O] . Raghuveer Singh Mali, Reuben Kapur 2013

机译：IS PI3激酶调节亚基在肥大细胞发育中的独特和冗余作用
7. Class IA PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes [O] . Krishnan, Subha, Mali, Raghuveer Singh, Koehler, Karl R., 2012

机译：IA类PI3激酶调节亚基p85α通过调节生长和存活相关基因介导肥大细胞发育。

Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development

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