...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Retinal cases & brief reports >ACUTE RETINAL NECROSIS SECONDARY TO MULTIDRUG-RESISTANT HERPES SIMPLEX VIRUS 2 IN AN IMMUNOCOMPETENT ADOLESCENT
【24h】

ACUTE RETINAL NECROSIS SECONDARY TO MULTIDRUG-RESISTANT HERPES SIMPLEX VIRUS 2 IN AN IMMUNOCOMPETENT ADOLESCENT

机译：免疫相容性青少年继发于多药耐药单纯疱疹病毒2的急性视网膜坏死

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: To report the clinical course of a patient with acute retinal necrosis resulting from a multidrug-resistant strain of herpes simplex virus 2. Methods: Observational case report. Results: A 17-year-old man with no identifiable immune deficiency presented with pain and decreased vision in his left eye. He had dense anterior and posterior segment inflammation with retinal whitening suggestive of acute retinal necrosis, which progressed despite treatment with intravenous acyclovir, methylprednisolone, and ganciclovir. A transition to intravitreal and intravenous foscarnet led to clinical improvement. Genetic analysis revealed the etiology to be a multidrug-resistant strain of herpes simplex virus 2. Conclusion: Antiviral resistance is an uncommon finding among viruses causing acute retinal necrosis in immunocompetent patients. Patients with these infections may be adequately treated with prompt recognition and a change in therapy to alternative antiviral agents such as foscarnet.
机译：目的：报告由单纯疱疹病毒2的多药耐药株导致的急性视网膜坏死患者的临床过程。方法：观察病例报告。结果：一名没有可识别的免疫缺陷的17岁男子左眼出现疼痛和视力下降。他患有密集的前，后节炎症，并伴有视网膜增白，提示急性视网膜坏死，尽管使用静脉注射阿昔洛韦，甲基强的松龙和更昔洛韦进行了治疗，但病情进展。向玻璃体内和静脉注射膦甲酸的过渡导致临床改善。遗传分析表明，病因是单纯疱疹病毒2的多药耐药株。结论：在具有免疫功能的患者中，引起急性视网膜坏死的病毒中很少发现抗病毒耐药性。患有这些感染的患者可能会得到迅速的识别，并且可以改用其他抗病毒药物（例如膦甲酸酯）进行适当的治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号