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An evaluation of dosimetric characteristics of MAGIC gel modified by adding formaldehyde (MAGIC-f)

机译：通过添加甲醛改性的MAGIC凝胶的剂量特性评估（MAGIC-f）

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摘要

Purpose: To evaluate the dosimetric characteristics of a new formulation of MAGIC gel, called MAGIC-f, which contains the addition of 3.3% formaldehyde, resulting in a gel with increased thermal stability. Methods: MAGIC-f gel was prepared and stored in hermetically sealed plastic containers. After irradiation, magnetic resonance images (MRI) were acquired to evaluate dose and dose distribution. Dosimetric characterization was performed by means of depth dose measurements, dose response sensitivity and linearity, temporal stability, energy and dose rate dependence, dose integration using sequential beams, temperature influence during MRI acquisition and dose distribution integrity. Results: MAGIC-f depth dose measurements are compatible with the dosimetric table data within ±4% uncertainty. The dosimeter's R_2 response varies linearly with dose at least from 0 to 6 Gy. The time-course of the sensitivity of the dosimeter following irradiation, indicated stabilization after 2 weeks. The dosimeter's response to irradiation was altered by 6% when increasing the energy from cobalt beams to 10 MV beams. The dose rate dependence of this new formulation of gel dosimeter is small: less than 2.5% for a variation from 200 to 500 cGy/min, and the dependence with the fractionation scheme is about 50% smaller than for standard MAGIC gel. The dependence on scanning temperature was also verified, and the integrity of the dose distribution was confirmed for a period of 90 days. Conclusions: The results demonstrate the applicability of this new dosimeter in tridimensional dose distribution measurements.
机译：目的：评估一种名为MAGIC-f的MAGIC凝胶新配方的剂量特性，该配方含有3.3％的甲醛，从而形成了具有更高热稳定性的凝胶。方法：制备MAGIC-f凝胶，并保存在密封的塑料容器中。照射后，获取磁共振图像（MRI）以评估剂量和剂量分布。剂量学表征通过深度剂量测量，剂量响应敏感性和线性，时间稳定性，能量和剂量率依赖性，使用顺序光束的剂量积分，MRI采集期间的温度影响和剂量分布完整性来进行。结果：MAGIC-f深度剂量测量值与剂量表数据兼容，不确定度为±4％。剂量计的R_2响应随剂量至少从0到6 Gy线性变化。辐射后剂量计灵敏度随时间变化，表明2周后稳定。当从钴束增加到10 MV束的能量时，剂量计对辐照的响应改变了6％。这种新的凝胶剂量计配方的剂量率依赖性很小：对于200至500 cGy / min的变化，小于2.5％，而分馏方案的依赖性比标准MAGIC凝胶小约50％。还验证了对扫描温度的依赖性，并在90天的时间内确认了剂量分布的完整性。结论：结果证明了这种新型剂量计在三维剂量分布测量中的适用性。

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