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Clinical COPD Questionnaire in -patients with chronic respiratory disease

机译：慢性呼吸道疾病患者的临床COPD问卷

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Background and objective: The Clinical Chronic Obstructive Pulmonary Disease (COPD) Questionnaire (CCQ) is an easy to complete, health-related quality of life questionnaire which has been well-validated in COPD. The responsiveness of the CCQ in chronic respiratory disease patients other than COPD has not been previously described. The study aims were to determine if the CCQ in chronic respiratory disease correlates with other health related quality of life questionnaires, to assess the responsiveness of the CCQ to pulmonary rehabilitation and to determine the minimum important difference. Methods: The CCQ, COPD Assessment Test (CAT), the Chronic Respiratory Questionnaire (CRQ) and St George's Respiratory Questionnaire (SGRQ) were measured in 138 chronic respiratory disease patients completing pulmonary rehabilitation. Change in CCQ with pulmonary rehabilitation was correlated with change in the other questionnaires. The minimum important difference of the CCQ was calculated using distribution and anchor-based approaches. Results: The CCQ, CAT, CRQ and SGRQ improved significantly with rehabilitation with effect sizes of -0.43, -0.26, 0.62, -0.37. Change in CCQ correlated significantly with CAT, CRQ and SGRQ (r = 0.53, -0.64, 0.30, allP < 0.0001).The minimum important difference was -0.42 at the population level and -0.4 at the individual level. Conclusions: The CCQ is responsive to pulmonary rehabilitation in chronic respiratory disease patients, with an MID estimated at -0.4 at the individual level.
机译：背景与目的：《临床慢性阻塞性肺疾病（COPD）调查表》（CCQ）是一种易于填写，与健康相关的生活质量调查表，已在COPD中得到了有效验证。先前没有描述慢性阻塞性肺病对慢性阻塞性肺病以外的慢性呼吸道疾病患者的反应。该研究的目的是确定慢性呼吸道疾病的CCQ是否与其他健康相关的生活质量调查表相关联，以评估CCQ对肺康复的反应性并确定最小的重要差异。方法：对138名完成肺康复的慢性呼吸系统疾病患者进行了CCQ，COPD评估测试（CAT），慢性呼吸问卷（CRQ）和圣乔治呼吸问卷（SGRQ）的测量。伴随肺康复的CCQ的变化与其他问卷的变化相关。使用分布和基于锚的方法计算出CCQ的最小重要差异。结果：随着康复，CCQ，CAT，CRQ和SGRQ显着改善，效果大小分别为-0.43，-0.26、0.62和-0.37。 CCQ的变化与CAT，CRQ和SGRQ显着相关（r = 0.53，-0.64，0.30，allP <0.0001）。最小重要差异在人群水平为-0.42，在个体水平为-0.4。结论：CCQ对慢性呼吸道疾病患者的肺部康复有反应，个体水平的MID估计为-0.4。

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