...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Resuscitation. >'Blind' transfusion of blood products in exsanguinating trauma patients.
【24h】

'Blind' transfusion of blood products in exsanguinating trauma patients.

机译：抽血的创伤患者被“盲目”输血。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: In trauma, as interventions are carried out to stop bleeding, ongoing resuscitation with blood products is of vital importance. As transfusion policy in exsanguinating patients cannot be based on laboratory tests, transfusion of blood products is performed empirically or 'blindly'. The aim of this study was to delineate 'blind' transfusion practice in the hectic clinical situation of exsanguination. METHODS: Seventeen trauma patients were selected who died due to uncontrolled bleeding despite haemostatic interventions within 24h after admission and who received more than 12 U of RBC. Transfusion data were compared with a theoretically optimal transfusion model with a fixed ratio between units of RBC, FFP, and platelets. The difference between the observed and expected amounts of blood products was calculated. RESULTS: The patients (82%) received insufficient amounts of FFP and platelets when compared to the calculated amounts. The total numbers of transfused FFP and platelets were on average 50% lower than the calculated amounts. Regression models showed an increase of FFP and platelets with increasing amounts of RBC but not in sufficient quantities. CONCLUSION: Exsanguinating trauma patients receiving massive transfusions are subject to 'blind' transfusion. This is associated with insufficient transfusion of both FFP and platelets, which may aggravate bleeding. A 'blind' transfusion strategy consisting of a validated guideline with a predefined ratio of the different blood products, timing of laboratory tests as well as a sound logistic protocol facilitating this procedure, involving the blood bank and treating physicians, is needed urgently.
机译：背景：在创伤中，由于采取了干预措施以止血，因此持续进行血液制品复苏至关重要。由于不能使实验室放血的输血策略不能基于实验室测试，因此血液产品的输血是凭经验或“盲目”进行的。这项研究的目的是在忙于放血的繁忙临床情况中描述“盲”输血实践。方法：选择入院后24小时内尽管进行了止血干预但因失控出血而死亡的17例创伤患者，并接受了12 U以上的RBC。将输血数据与理论上最佳的输血模型进行比较，该模型在RBC，FFP和血小板单位之间具有固定比率。计算观察到的和预期的血液制品量之间的差异。结果：与计算量相比，患者（82％）接受的FFP和血小板量不足。输注的FFP和血小板总数平均比计算值低50％。回归模型显示，随着红细胞数量的增加，FFP和血小板增加，但数量不足。结论：使大量输血的创伤患者失去知觉，会遭受“盲目”输血。这与FFP和血小板的输血不足有关，可能加剧出血。迫切需要一种“盲”输血策略，其中包括经过验证的指南以及不同血液产品的预定义比例，实验室测试的时间安排以及有助于该程序的完善的后勤协议（涉及血库和治疗医师）。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号