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首页> 外文期刊>Respirology : >Changes in lung function and tidal airflow patterns after increasing extrathoracic airway resistance.
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Changes in lung function and tidal airflow patterns after increasing extrathoracic airway resistance.

机译：胸外气道阻力增加后，肺功能和潮气变化。

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Changes in lung function and tidal airflow patterns after increasing extrathoracic airway resistance MORRIS MJ, WILLIAMS EM, MADGWICK RG, BANERJEE R, PHILLIPS EL. Respirology 2004; 9: 474-480Objective: The aim of this study was to determine what changes occur in previously described tidal expiratory flow patterns when extrathoracic resistance is added. Methodology: A total of 16 subjects with normal lung function and 15 patients with chronic COPD, were studied. The following measurements were made before and after the addition of an extrathoracic expiratory resistance (EER; 0.89 kPa/L s at a flow of 0.5 L/s) during uncoached tidal breathing: expiratory time (t(E)), frequency (f), expiratory time to maximum flow/total expiratory time (t(PTEF)/t(E)), tidal maximum expiratory flow (PEF(TIDAL)), and time constant of the respiratory system calculated from the passive portion of tidal expiration (trs(TIDAL)). Post peak profiles were categorized as convex, linear or concave and time for flow to fall to 80% and 20% of maximum (t(80) and t(20)) were measured. Results: Tidal indices t(E), f and PEF(TIDAL), were similar in the two groups, but t(PTEF)/t(E) was greater and trs(TIDAL) was less in the normal subjects than in the COPD patients. Addition of EER in both groups caused PEF(TIDAL) to decrease and trs(TIDAL), t(80) and the percentage of convex profiles to increase. t(PTEF)/t(E) increased in the COPD patients but was unchanged in the control group. Conclusion: After addition of EER during tidal breathing, expiratory flow in COPD patients resembled that seen in normal subjects.
机译：胸外气道阻力增加后，肺功能和潮气流动方式的变化。MORRIS MJ，WILLIAMS EM，MADGWICK RG，BANERJEE R和PHILLIPS EL。呼吸学2004; 9：474-480目的：这项研究的目的是确定当增加胸外阻力时，先前描述的潮气呼气流动模式发生了什么变化。方法：共研究了16名肺功能正常的受试者和15名慢性COPD患者。在未进行潮气训练时，在增加胸外呼气阻力（EER; 0.5 L / s的流量时为0.89 kPa / L s）之前和之后进行以下测量：呼气时间（t（E）），频率（f） ，到最大流量的呼气时间/总呼气时间（t（PTEF）/ t（E）），潮气最大呼气流量（PEF（TIDAL））和根据潮气呼气的被动部分计算的呼吸系统时间常数（trs （潮汐））。峰后轮廓分为凸形，线性或凹形，并测量流量下降到最大值的80％和20％（t（80）和t（20））的时间。结果：两组的潮气指数t（E），f和PEF（TIDAL）相似，但正常人的t（PTEF）/ t（E）更大，trs（TIDAL）小于COPD耐心。两组中EER的增加导致PEF（TIDAL）降低，trs（TIDAL），t（80）和凸轮廓的百分比增加。 COPD患者的t（PTEF）/ t（E）升高，而对照组则没有变化。结论：潮气呼吸中加入EER后，COPD患者的呼气流量与正常人相似。

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