Does pesticide risk assessment in the European Union assess long-term effects?

Newman MC; Crane M; Holloway G

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Does pesticide risk assessment in the European Union assess long-term effects?

机译：欧盟的农药风险评估是否评估长期影响？

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Current methods would allow reasonable predictions of long-term effects of pesticide application if three changes were instituted. First, more population-based laboratory studies should be applied in predictive pesticide risk assessment. Second, ERA should include as much effort on collating and integrating ecological knowledge into the assessment in Tier 1 as is currently expended on gathering chemical and toxicological information on exposure and effects. Production of a formal conceptual ecological risk assessment model for each product or active substance for which authorization is sought would provide an appropriate framework for integrating and applying such knowledge. Third, in acknowledgment of the uncertainties in the predictive risk assessment process, more postauthorization monitoring should be done. The application of Occam's razor to pesticide risk assessment makes good sense, as it does in any other field of science. However, we must take care that simplicity in risk assessment process does not lead to oversimplification: Essentially all science is the study of either very small bits of reality or simplified surrogates for complex whole systems. How we simplify can be critical. Careless simplification leads to misleading simplistic conclusions. (Slobodkin 1994).

机译：如果采取了三项措施，目前的方法将能够合理预测农药施用的长期影响。首先，应在预测性农药风险评估中应用更多基于人群的实验室研究。其次，与目前在收集有关暴露和影响的化学和毒理学信息上所花费的精力一样，ERA应该在将生态知识整理和整合到方法1中的评估上付出最大的努力。为每种产品或活性物质申请正式的概念生态风险评估模型，将为整合和应用此类知识提供适当的框架。第三，在确认预测风险评估过程中存在不确定性时，应进行更多的授权后监测。像其他任何科学领域一样，将Occam剃刀应用于农药风险评估是很有意义的。但是，我们必须注意，风险评估流程的简化不会导致过分简化：本质上，所有科学都是对现实的很小一部分或对复杂的整个系统的简化替代的研究。我们如何简化可能至关重要。粗心的简化会导致误导性的简单化结论。（Slobodkin 1994）。

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《Reviews of environmental contamination and toxicology》 |2006年第0期|共65页
作者
Newman MC; Crane M; Holloway G;
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正文语种 eng
中图分类药学;
关键词
Risk Assessment; Pesticides; predictive; Exertional dyspnea; 危险性评估; 农药;

机译：Risk Assessment;Pesticides;predictive;Exertional dyspnea;危险性评估;农药;

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1. Does pesticide risk assessment in the European Union assess long-term effects? [J] . Newman MC, Crane M, Holloway G Reviews of environmental contamination and toxicology . 2006,第0期

机译：欧盟的农药风险评估是否评估长期影响？
2. Scientific risk assessment of pesticides in the European Union (EU): EFSA contribution to on‐going reflections by the EC [J] . EFSA supporting publications . 2018,第1期

机译：欧盟（EU）中农药的科学风险评估：EFSA对EC正在进行的反思的贡献
3. European Union:Pesticides: Breakthrough on Cumulative Risk Assessment [J] . World Food Regulation Review . 2016,第9期

机译：欧盟：农药：累积风险评估的突破
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Does pesticide risk assessment in the European Union assess long-term effects?

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