...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Respirology : >Predicting the response to air travel in passengers with non-obstructive lung disease: are the current guidelines appropriate?
【24h】

Predicting the response to air travel in passengers with non-obstructive lung disease: are the current guidelines appropriate?

机译：预测非阻塞性肺疾病乘客对空中旅行的反应：当前的指南是否合适？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND AND OBJECTIVE: Air travel guidelines recommend using baseline arterial oxygen levels and the hypoxic challenge test (HCT) to predict in-flight hypoxaemia and the requirement for in-flight oxygen in patients with lung disease. The purpose of the present study was to (i) quantify the hypoxaemic response to air travel and (ii) identify baseline correlate(s) to predict this response in passengers with non-obstructed lung disease. METHODS: Fourteen passengers (seven women) with chronic non-obstructed lung disease volunteered for this study. The study involved three phases: (i) respiratory function testing; (ii) in-flight measures (SpO(2), cabin pressure and dyspnoea); and (iii) a HCT. The in-flight hypoxaemic response was compared with the baseline arterial oxygen level, respiratory function and the HCT. RESULTS: All subjects flew without oxygen and no adverse events were recorded in-flight. Mean cabin pressure was 593 +/- 16 mm Hg. Pre-flight SpO(2) was 95 +/- 3% and significantly decreased to 85 +/- 9% in-flight, with further significant falls in subjects who walked during the flight (nadir SpO(2) 78 +/- 11%). The pre-flight SpO(2) showed the strongest correlation with in-flight SpO(2) (r = 0.91, P < 0.001). The HCT SpO(2) was moderately correlated to the in-flight SpO(2) (r = 0.58, P < 0.05). Spirometry, D(L,CO) and TLC measurements did not correlate with in-flight SpO(2). CONCLUSION: Significant in-flight desaturation can be expected in passengers with non-obstructive lung disease. Respiratory function did not predict in-flight desaturation. We found a good relationship between pre-flight SpO(2) and in-flight SpO(2) which supports the role of pre-flight oximetry for predicting in-flight hypoxaemia in passengers with non-obstructed lung disease.
机译：背景与目的：航空旅行指南建议使用基线动脉血氧水平和低氧激发试验（HCT）来预测肺部疾病患者的机舱低氧血症和机舱氧气需求。本研究的目的是（i）量化对航空旅行的低氧血症反应，（ii）确定基线相关因素以预测患有非阻塞性肺病的乘客的这种反应。方法：十四名患有慢性非阻塞性肺疾病的乘客（七名妇女）自愿参加了这项研究。该研究涉及三个阶段：（i）呼吸功能测试; （ii）机上措施（SpO（2），机舱压力和呼吸困难）; （iii）HCT。将飞行中的低氧血症反应与基线动脉血氧水平，呼吸功能和HCT进行比较。结果：所有受试者在没有氧气的情况下飞行，并且没有在飞行中记录到不良事件。平均舱室压力为593 +/- 16毫米汞柱。飞行前SpO（2）为95 +/- 3％，飞行中显着降低至85 +/- 9％，飞行过程中行走的对象进一步下降（天底SpO（2）78 +/- 11 ％）。飞行前SpO（2）显示与飞行中SpO（2）的相关性最强（r = 0.91，P <0.001）。 HCT SpO（2）与飞行中SpO（2）呈中等相关性（r = 0.58，P <0.05）。肺活量测定，D（L，CO）和TLC测量与飞行中SpO（2）不相关。结论：患有非阻塞性肺疾病的乘客可望在飞行中出现明显的去饱和。呼吸功能不能预测飞行中的饱和度。我们发现飞行前SpO（2）和飞行中SpO（2）之间存在良好的关系，该关系支持飞行前血氧饱和度预测非阻塞性肺病乘客飞行中低氧血症的作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号