The role of microRNAs in respiratory viral infection: friend or foe?

Tahamtan Alireza; Inchley Christopher S.; Marzban Mona; Tavakoli-Yaraki Masoumeh; Teymoori-Rad Majid; Nakstad Britt; Salimi Vahid

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The role of microRNAs in respiratory viral infection: friend or foe?

机译：microRNA在呼吸道病毒感染中的作用：是敌还是友？

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MicroRNAs (miRNAs) have emerged as a class of regulatory RNAs in host-pathogen interactions. Aberrant miRNA expression seems to play a central role in the pathology of several respiratory viruses, promoting development and progression of infection. miRNAs may thus serve as therapeutic and prognostic factors for respiratory viral infectious disease caused by a variety of agents. We present a comprehensive review of recent findings related to the role of miRNAs in different respiratory viral infections and discuss possible therapeutic opportunities aiming to attenuate the burden of viral infections. Our review supports the emerging concept that cellular and viral-encoded miRNAs might be broadly implicated in human respiratory viral infections, with either positive or negative effects on virus life cycle. Copyright (c) 2016 John Wiley & Sons, Ltd.

机译：在宿主-病原体相互作用中，MicroRNA（miRNA）已成为一类调节性RNA。异常的miRNA表达似乎在几种呼吸道病毒的病理学中起着核心作用，促进了感染的发生和发展。因此，miRNA可以作为由多种药物引起的呼吸道病毒感染性疾病的治疗和预后因素。我们提出了与miRNA在不同的呼吸道病毒感染中的作用有关的最新发现的全面综述，并讨论了旨在减轻病毒感染负担的可能的治疗机会。我们的评论支持新出现的概念，即细胞和病毒编码的miRNA可能广泛涉及人类呼吸道病毒感染，对病毒生命周期具有正向或负向影响。版权所有（c）2016 John Wiley＆Sons，Ltd.

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《Reviews in medical virology》 |2016年第6期|共19页
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Tahamtan Alireza; Inchley Christopher S.; Marzban Mona; Tavakoli-Yaraki Masoumeh; Teymoori-Rad Majid; Nakstad Britt; Salimi Vahid;
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正文语种 eng
中图分类医学微生物学（病原细菌学、病原微生物学）;
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入库时间 2022-08-18 13:36:27

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1. The role of microRNAs in respiratory viral infection: friend or foe? [J] . Tahamtan Alireza, Inchley Christopher S., Marzban Mona, Reviews in medical virology . 2016,第6期

机译：microRNA在呼吸道病毒感染中的作用：是敌还是友？
2. Cellular senescence: friend or foe to respiratory viral infections? [J] . William J. Kelley, Rachel L. Zemans, Daniel R. Goldstein The European respiratory journal : . 2020,第6期

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3. The protective and pathogenic roles of IL-17 in viral infections: friend or foe? [J] . Ma Wen-Tao, Yao Xiao-Ting, Peng Qun, Open Biology . 2019,第7期

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4. Viral Etiological Studies for Acute Respiratory Infections in Children During SARS Epidemic in Beijing [C] . . -1

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5. Evaluating the severity of acute respiratory infections: Advantage of meditation over exercise; Viral and bacterial co-infection; and Reduction of Wisconsin Upper Respiratory Symptom Survey. [D] . Obasi, Chidi N. 2012

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8. Increased Susceptibility to Pentobarbital Following Mouse Cytomegalovirus Infection: Relative Roles of Viral-Induced Interferon and Viral Infection of the Liver [R] . Catignani, J. C., Menache, M. G., Selgrade, M. K. 1989

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The role of microRNAs in respiratory viral infection: friend or foe?

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