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Lack of osmosensitive CD9 expression in rat liver cells.

机译:大鼠肝细胞中缺乏渗透敏感性CD9表达。

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摘要

CD9 mRNA was found to be strongly expressed in H4IIE rat hepatoma cells and rat liver macrophages (Kupffer cells), whereas the expression was weak in primary rat liver parenchymal cells. An osmosensitive regulation of CD9 mRNA levels was not detectable in all three cell types, whereas this has recently been described for Madin Darby canine kidney cells and rabbit renal papillary cells (see text). The findings suggest that osmoregulation of specific genes may exhibit cell type specificity.
机译:发现CD9 mRNA在H4IIE大鼠肝癌细胞和大鼠肝巨噬细胞(库普弗细胞)中强烈表达,而在原代大鼠肝实质细胞中表达较弱。在所有三种细胞类型中均未检测到CD9 mRNA水平的渗透敏感性调节,而最近已对Madin Darby犬肾细胞和兔肾乳头细胞进行了描述(参见文本)。这些发现提示特定基因的渗透调节可能表现出细胞类型特异性。

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