...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Rheumatic diseases clinics of North America >Outcome assessment in the adult and juvenile idiopathic inflammatory myopathies.
【24h】

Outcome assessment in the adult and juvenile idiopathic inflammatory myopathies.

机译：成人和青少年特发性炎症性肌病的结果评估。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Through the recent efforts of multi-center collaborative study groups, a number of measures have been developed and partially validated to assess disease activity, disease damage, and health-related quality of life in adult and juvenile patients with IIM. Preliminary core set domains and core set measures of activity and damage have also been developed for adult and juvenile patients with myositis. Validated definitions of improvement and disability should be forthcoming in the next few years. These extraordinary developments will enable much-needed standardization in the assessment of the IIM, particularly in therapeutic and other clinical research studies. Despite this substantial progress, there is a need to develop more sensitive measures to assess IIM disease activity and damage, to further validate the existing tools, to define their performance characteristics in various IIM subgroups, to develop improved imaging techniques that are also quantitative, and to validate activation markers as surrogate measures. The ongoing cooperation of multiple specialists with expertise in these disorders, combined with emerging novel technologies, should continue to enhance the assessment of myositis. Improved clinical care and more rapid development of new therapies for patients with myositis will be the ultimate gains realized from these efforts.
机译：通过多中心协作研究小组的最新努力，已开发出许多措施并进行了部分验证，以评估IIM成人和青少年患者的疾病活动，疾病损害和与健康相关的生活质量。还已经为成年和青少年肌炎患者开发了初步的核心集域以及活动和损害的核心集度量。经过验证的改善和残疾定义将在未来几年内出现。这些非凡的发展将使IIM评估中急需的标准化，尤其是在治疗和其他临床研究中。尽管取得了重大进展，但仍需要开发更敏感的措施来评估IIM疾病活动和损害，进一步验证现有工具，定义其在各种IIM亚组中的性能特征，开发改进的定量成像技术，以及验证激活标记作为替代措施。具有这些疾病专业知识的多位专家的持续合作，再加上新兴的新技术，应继续加强对肌炎的评估。通过这些努力，最终的成果将是为肌炎患者改善临床护理并加快新疗法的开发速度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号