• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Inorganic microcapsules mineralized at the interface of water droplets in ethanol solution and their application as drug carriers
【24h】

Inorganic microcapsules mineralized at the interface of water droplets in ethanol solution and their application as drug carriers

机译：乙醇溶液中水滴界面矿化的无机微囊及其作为药物载体的应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This paper reported a crystallization -dissolution -interface mineralization (CDIM) method on synthesizing calcium carbonate (CaC) and calcium phosphate (CaP) inorganic microcapsules with good biocompatibility and good pH sensitivity. The method is based on mineralization at the ethanol/water interface. The microcapsules were formed in a few seconds and did not need post treatment for removing the templates. The diameters of the microcapsules can be controlled by the size of the crystal clusters regulated by stirring time. Carboxyfluorescein (CF) molecules as model drugs were encapsulated inside the capsules after coating with Fe-III-polyphenol tannic acid (TA) films. The pH sensitive carboxyfluorescein molecule releasing behavior was investigated. The lower pH caused faster and thorough release of CF. The CDIM method can be applied for fabricating other inorganic microcapsules, which holds great potential for drug delivery.
机译：本文报道了一种结晶-溶解-界面矿化法（CDIM），用于合成具有良好生物相容性和良好pH敏感性的碳酸钙（CaC）和磷酸钙（CaP）无机微胶囊。该方法基于乙醇/水界面的矿化作用。微胶囊在几秒钟内形成，不需要后处理即可除去模板。微胶囊的直径可以通过搅拌时间调节的晶体簇的大小来控制。在用Fe-III-多酚单宁酸（TA）膜包衣后，将作为模型药物的羧基荧光素（CF）分子封装在胶囊内。研究了pH敏感的羧基荧光素分子的释放行为。较低的pH值导致CF更快，更彻底地释放。 CDIM方法可用于制造其他无机微胶囊，具有很大的药物输送潜力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号