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首页> 外文期刊>RSC Advances >A triphenylamine-based colorimetric and 'turn-on' fluorescent probe for detection of cyanide anions in live cells
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A triphenylamine-based colorimetric and 'turn-on' fluorescent probe for detection of cyanide anions in live cells

机译：基于三苯胺的比色和“开启”荧光探针，用于检测活细胞中的氰化物阴离子

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摘要

A colorimetric and "turn-on" fluorescent probe has been developed for the detection of cyanide anions. Cyanide was detected via the nucleophilic addition of cyanide to the indolium group of the probe, which resulted in a change from a purple colour to colourless and an enhancement in fluorescence. The probe showed a high sensitivity and selectivity for cyanide anions over other common anionic species in aqueous ethanol solution. The limit of detection was as low as 21 nM. A live cell imaging experiment demonstrated the practical value of this probe in tracing cyanide anions in biological systems.
机译：已开发出一种比色和“开启”荧光探针，用于检测氰化物阴离子。通过将氰化物亲核加成到探针的吲哚基团中可以检测到氰化物，从而导致从紫色变为无色并增强了荧光。该探针对乙醇水溶​​液中的氰化物阴离子显示出比其他常见阴离子更高的灵敏度和选择性。检测限低至21 nM。活细胞成像实验证明了该探针在生物系统中追查氰化物阴离子的实用价值。

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