• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >A quinazoline derivative as quick-response red-shifted reporter for nanomolar Al3+ and applicable to living cell staining
【24h】

A quinazoline derivative as quick-response red-shifted reporter for nanomolar Al3+ and applicable to living cell staining

机译：喹唑啉衍生物作为纳摩尔Al3 +的快速反应红移报告分子，适用于活细胞染色

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A newly synthesized and structurally characterized quinazoline derivative (L) has been shown to act as a quick-response chemosensor for Al3+ with a high selectivity over other metal ions in water-DMSO. In the presence of Al3+, L shows a red-shifted ratiometric enhancement in fluorescence as a result of internal charge transfer and chelation-enhanced fluorescence through the inhibition of a photo-induced electron transfer mechanism. This probe detects Al3+ at concentrations as low as 1.48 nM in 100 mM HEPES buffer (DMSO-water, 1 : 9 v/v) at biological pH with a very short response time (15-20 s). L was applied to biological imaging to validate its utility as a fluorescent probe for monitoring Al3+ ions in living cells, illustrating its value in practical environmental and biological systems.
机译：一种新合成且结构表征的喹唑啉衍生物（L）已显示出对Al3 +的快速响应化学传感器的作用，对水-DMSO中的其他金属离子具有高选择性。在存在Al3 +的情况下，由于内部电荷转移和通过抑制光诱导的电子转移机制，螯合增强的荧光，L在荧光上显示出红移的比例增强。该探针在生物学pH下以非常短的响应时间（15-20 s）在100 mM HEPES缓冲液（DMSO-水，1：9 v / v）中检测到低至1.48 nM的Al3 +。 L应用于生物成像，以验证其作为监测活细胞中Al3 +离子的荧光探针的实用性，从而说明了其在实际环境和生物系统中的价值。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号