• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Biological and pharmacological activities of amaryllidaceae alkaloids
【24h】

Biological and pharmacological activities of amaryllidaceae alkaloids

机译：芳科植物生物碱的生物和药理活性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The amaryllidaceae family consists of about 75 genera and 1100 species that are wide-spread in the tropics and warm temperate regions of the world. Since the first isolation of lycorine, more than 500 amaryllidaceae alkaloids have been isolated over the past three decades. The enormous numbers of diverse amaryllidaceae alkaloids are classified into different groups mainly according to their structural features. The representative alkaloids are norbelladine, lycorine, hippeastrine, narwedine, haemanthamine, pancratistatin, pretazettine, montanine, galanthindole, cherylline and ismine. Recently, more extensive studies have revealed that amaryllidaceae alkaloids exhibit a wide range of bioactivities, such as antitumor, antiviral, antibacterial, antifungal, antimalarial and analgesic. Acetylcholinesterase (AChE) inhibitory and cytotoxic activities have also been reported. The aim of the present review is to discuss the recent developments on the biological and pharmacological activities of amaryllidaceae alkaloids with IC50 or EC50 values since 2005, supporting the potential therapeutic possibilities for the use of these compounds.
机译：石蒜科由大约75属和1100种组成，广泛分布于世界热带和温带地区。自从首次分离出lycorine以来，在过去的三十年中已分离出500多种芳基科的生物碱。主要根据其结构特征将大量不同的芳科植物生物碱分为不同的组。代表性的生物碱为去甲苦参碱，赖氨酸，马斯匹林，纳尔维定，甘露明，潘克拉斯汀，普他他汀，单宁，加兰噻吩，黑麦草碱和亚胺。最近，更广泛的研究表明，芳科植物生物碱具有广泛的生物活性，例如抗肿瘤，抗病毒，抗菌，抗真菌，抗疟疾和镇痛。乙酰胆碱酯酶（AChE）的抑制和细胞毒活性也已有报道。本综述的目的是讨论自2005年以来具有IC50或EC50值的芳草科生物碱的生物和药理活性的最新进展，支持使用这些化合物的潜在治疗可能性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号