Self-assembled amphoterecin B loaded into a self-assembled cardanol derivative as a soft green carrier for delivery and enhanced antifungal activity

Mahata Denial; Mandal Santi M.; Nando Golok B.

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Self-assembled amphoterecin B loaded into a self-assembled cardanol derivative as a soft green carrier for delivery and enhanced antifungal activity

机译：将自组装的两性霉素B装入作为软绿色载体的自组装腰果酚衍生物中，以进行递送并增强抗真菌活性

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Self-assembly strategies are used for soft green carrier (SGC) preparation from cardanol after modification with benzenediazonium functional moieties (PHPDB). A spherical core-shell like self-assembled structure of Amphotericin B (AmpB) was loaded into PHPDB and released in aqueous medium. AmpB and PHPDB show ergosterol and chitin binding affinity, respectively, and sustain enhanced activity with proficient biofilm eradication.

机译：自组装策略用于在用苯重氮官能团（PHPDB）改性后从腰果酚制备软绿色载体（SGC）。将两性霉素B（AmpB）的球形核壳状自组装结构加载到PHPDB中，并在水性介质中释放。 AmpB和PHPDB分别显示出麦角固醇和几丁质的结合亲和力，并通过有效的生物膜根除而维持增强的活性。

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《RSC Advances》 |2014年第89期|共4页
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Mahata Denial; Mandal Santi M.; Nando Golok B.;
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1. Self-assembled amphoterecin B loaded into a self-assembled cardanol derivative as a soft green carrier for delivery and enhanced antifungal activity [J] . Mahata Denial, Mandal Santi M., Nando Golok B. RSC Advances . 2014,第89期

机译：将自组装的两性霉素B装入作为软绿色载体的自组装腰果酚衍生物中，以进行递送并增强抗真菌活性
2. Miconazole-loaded nanostructured lipid carriers (NLC) for local delivery to the oral mucosa: Improving antifungal activity [J] . Mendes A.I., Silva A.C., Catita J.A.M., Colloids and Surfaces, B. Biointerfaces . 2013,第Null期

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3. Drug carrier systems made from self-assembled glyco-nanoparticles of maltoheptaose-b-polyisoprene enhanced the distribution and activity of curcumin against cancer cells [J] . Caldas Barbara Sthefani, Lazarin-Bidoia Danielle, Nakamura Celso Vataru, Journal of Molecular Liquids . 2020,第1期

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4. Self-Assembled Micellar Complex Comprised of Green Tea Catechin Derivatives for Protein Drug Delivery [C] . Susi Tan, Joo Eun Chung, Shu Jun Gao, Society for Biomaterials annual meeting and exposition . 2013

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Self-assembled amphoterecin B loaded into a self-assembled cardanol derivative as a soft green carrier for delivery and enhanced antifungal activity

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