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Nanosheet-based 3D hierarchical ZnO structure decorated with Au nanoparticles for enhanced electrochemical detection of dopamine

机译:基于纳米片的3D分层ZnO结构,以Au纳米颗粒修饰,用于增强多巴胺的电化学检测

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摘要

A biocompatible Au-ZnO nanocomposite was used to fabricate a sensitive sensor for the detection of dopamine (DA). High-density Au nanoparticles (AuNPs) were homogeneously loaded onto a nanosheet-based three-dimensionally (3D) hierarchical ZnO matrix. The high specific surface area of the nanosheetbased three-dimensionally (3D) hierarchical ZnO favored the high density loading of AuNPs, which helped efficiently catalyze the oxidation of DA. The Au-ZnO nanocomposite was characterized by scanning electron microscopy (SEM), energy dispersive spectrometry (EDS), transmission electron microscopy (TEM), X-ray powder diffraction (XRD) and electrochemical impedance spectroscopy (EIS). The electrocatalytic activity toward the oxidation of dopamine was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The sensors exhibited sensitive responses to DA with a linear range of 0.1-300 mu M and a detection limit of 0.02 mu M based on S/N = 3. The good analytical performance and long-term stability of the proposed sensor can be attributed to the synergistic effect of the nanosheet-based ZnO structure and gold nanoparticles on the electrochemical oxidation of dopamine.
机译:使用生物相容的Au-ZnO纳米复合材料来制造用于检测多巴胺(DA)的灵敏传感器。高密度金纳米粒子(AuNPs)被均匀地加载到基于纳米片的三维(3D)分层ZnO矩阵上。纳米片基三维(3D)分层ZnO的高比表面积有利于AuNPs的高密度负载,这有助于有效催化DA的氧化。 Au-ZnO纳米复合材料的特征在于扫描电子显微镜(SEM),能量色散光谱(EDS),透射电子显微镜(TEM),X射线粉末衍射(XRD)和电化学阻抗谱(EIS)。通过循环伏安法(CV)和微分脉冲伏安法(DPV)研究了对多巴胺氧化的电催化活性。传感器对DA表现出敏感的响应,线性范围为0.1-300μM,基于S / N = 3的检测极限为0.02μM。建议的传感器的良好分析性能和长期稳定性可以归因于纳米片基ZnO结构和金纳米颗粒对多巴胺电化学氧化的协同作用。

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