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首页> 外文期刊>Revue Francophone des laboratoires >Crystalluria: A marker for diagnosis and prognosis of crystallogenic pathologies and nephrolithiasis [La cristallurie: un marqueur diagnostique et pronostique des pathologies cristallogènes et des lithiases rénales]
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Crystalluria: A marker for diagnosis and prognosis of crystallogenic pathologies and nephrolithiasis [La cristallurie: un marqueur diagnostique et pronostique des pathologies cristallogènes et des lithiases rénales]

机译:结晶尿:结晶性病理和肾结石的诊断和预后标志物[结晶尿:结晶性病理和肾结石的诊断和预后标志物]

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摘要

Crystalluria: a marker for diagnosis and prognosis of crystallogenic pathologies and nephrolithiasis Crystalluria means that crystals are present in urine. Crystalluria is the result of urine supersaturation as regard one or several poorly soluble chemical species. Crystals found in urine as well as their morphological characteristics, their abundance, their occurrence as assessed from serial urine samples examination may provide useful information on metabolic factors or pathologies involved in crystal formation and able to induce stone formation and/or chronic renal failure. Identifying some typical crystals may orient immediately toward specific diagnosis such as tubular disorders or enzyme dysfunctions. The calculation of crystal volume from crystalluria parameters may help to optimize medical therapy in specific clinical situations. The disappearance of crystalluria during the clinical follow-up is probably the best criteria for assessing the efficacy of diet recommendations or drug therapy proposed to avoid stone recurrence in nephrolithiasis.
机译:结晶尿:结晶性病理和肾结石的诊断和预后标记结晶尿意味着尿液中存在晶体。就一种或几种难溶性化学物质而言,结晶尿是尿液过饱和的结果。尿液中发现的晶体及其形态特征,丰度,从连续尿液样本检查中评估的出现可能提供有关晶体形成所涉及的代谢因子或病理学的有用信息,并能够诱导结石形成和/或慢性肾衰竭。鉴定一些典型的晶体可能会立即针对特定的诊断,例如肾小管疾病或酶功能障碍。根据结晶度参数计算晶体体积可能有助于优化特定临床情况下的药物治疗。临床随访过程中结晶尿的消失可能是评估饮食建议或建议的治疗方法的最佳标准,以避免在肾结石症中结石复发。

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