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首页> 外文期刊>Occupational and environmental medicine >Pneumoconiosis and emphysema in construction workers: results of HRCT and lung function findings.
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Pneumoconiosis and emphysema in construction workers: results of HRCT and lung function findings.

机译：建筑工人中的尘肺和肺气肿：HRCT和肺功能检查结果。

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OBJECTIVES: To evaluate the prevalence of HRCT findings in construction workers previously surveyed by chest radiographs classified according to ILO guidelines. To examine the association between HRCT findings and exposure to quartz containing dust, and lung function. METHODS: The study comprised a questionnaire, dynamic and static lung function measurements, single-breath CO diffusion capacity, chest radiographs and HRCT in 79 individuals. Certified 'B' readers coded radiographs according to the ILO classification. HRCT scans were read according to an international classification system. A qualitative exposure index for cumulative respiratory quartz on a 10-point scale was used. RESULTS: Agreement between HRCT readers was good (kappa>0.60), except for irregular opacities (kappa=0.23). In ILO category 0/0, 8% HRCT round, 22% irregular and/or linear opacities and 41% HRCT emphysema was found. HRCT round opacities was associated with high cumulative quartz exposure (OR 7.1; 95% CI 1.3 to 37.8). Emphysema was associated with smoking (OR 10.1; 95% CI 1.2 to 84.2) and showed a reduction in T(L,CO,sb). HRCT round opacities was not associated with lung function. Current smoking was negatively associated with FEV/FVC ratio and positively with RV/TLC ratio, and showed a reduction in T(L,CO,sb) (13.4%), adjusted for different HRCT findings. CONCLUSIONS: Low grade silicosis cannot be excluded in workers with normal chest radiographs (ILO 0/0). In relatively highly exposed construction workers, a sevenfold increased risk of simple (nodular) silicosis was found. Emphysema on HRCT was associated with current or former smokers, but not with exposure, and contributed to reduced diffusion capacity. Airflow limitation was mainly determined by current smoking and was not associated with simple (nodular) silicosis.
机译：目的：评估先前根据国际劳工组织指南分类的胸部X光片对建筑工人进行HRCT检查的结果。检查HRCT结果与暴露于含有尘埃的石英和肺功能之间的关系。方法：该研究包括79名患者的问卷，动态和静态肺功能测量，单次呼吸CO扩散能力，胸部X光片和HRCT。合格的“ B”类阅读器根据国际劳工组织分类对射线照相进行编码。根据国际分类系统读取HRCT扫描。使用累积呼吸石英的定性暴露指数为10分制。结果：HRCT读者之间的一致性很好（kappa> 0.60），但不规则混浊（kappa = 0.23）除外。在国际劳工组织的0/0类中，发现8％的HRCT圆形，22％的不规则和/或线性不透明度和41％的HRCT肺气肿。 HRCT浑浊与高累积石英暴露量有关（OR 7.1; 95％CI 1.3至37.8）。肺气肿与吸烟有关（OR 10.1; 95％CI 1.2至84.2）并显示T（L，CO，sb）降低。 HRCT浑浊与肺功能无关。当前吸烟与FEV / FVC比值呈负相关，与RV / TLC比值呈正相关，并且根据不同的HRCT结果调整后，T（L，CO，sb）降低（13.4％）。结论：胸部X光片正常（ILO 0/0）的工人不能排除低度矽肺病。在相对高暴露的建筑工人中，发现单纯性（结节性）矽肺病的风险增加了七倍。 HRCT引起的肺气肿与现在或以前的吸烟者有关，但与暴露者无关，并导致扩散能力降低。气流受限主要由当前吸烟决定，与单纯性（结节性）矽肺病无关。

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