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首页> 外文期刊>Occupational and environmental medicine >Prospective study of hepatic, renal, and haematological surveillance in hazardous materials firefighters.
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Prospective study of hepatic, renal, and haematological surveillance in hazardous materials firefighters.

机译：危险材料消防员的肝，肾和血液学监测的前瞻性研究。

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OBJECTIVES: To evaluate possible health effects related to work with hazardous materials as measured by end organ effect markers in a large cohort over about 2 years, and in a subcohort over 5 years. METHODS: Hepatic, renal, and haematological variables were analysed from 1996-98 in hazardous materials firefighters including 288 hazardous materials technicians (81%) and 68 support workers (19%). The same end organ effect markers in a subcohort of the technicians were also analysed (n=35) from 1993-98. Support workers were considered as controls because they are also firefighters, but had a low potential exposure to hazardous materials. RESULTS: During the study period, no serious injuries or exposures were reported. For the end organ effect markers studied, no significant differences were found between technicians and support workers at either year 1 or year 3. After adjustment for a change in laboratory, no significant longitudinal changes were found within groups for any of the markers except for creatinine which decreased for both technicians (p<0.001) and controls (p<0.01). CONCLUSIONS: Health effects related to work are infrequent among hazardous materials technicians. Haematological, hepatic, and renal testing is not required on an annual basis and has limited use in detecting health effects in hazardous materials technicians.
机译：目的：评估在大型人群中（约两年以上）和在一个亚人群中（超过五年），通过终端器官效应标记物测量与使用危险材料有关的可能的健康影响。方法：分析了1996-98年危险材料消防员的肝，肾和血液学变量，其中包括288名危险材料技术人员（81％）和68名辅助人员（19％）。还分析了1993-98年间在技术人员小组中相同的末端器官效应标记（n = 35）。支持人员被认为是控制人员，因为他们也是消防员，但接触有害物质的可能性很小。结果：在研究期间，没有严重受伤或暴露的报道。对于所研究的终末器官效应标志物，技术人员和支持人员在第1年或第3年没有发现显着差异。根据实验室的变化进行调整后，除肌酐外，其他任何标志物在组内均未发现明显的纵向变化。技术人员（p <0.001）和对照组（p <0.01）均下降。结论：与工作有关的健康影响在危险材料技术人员中很少见。不需要每年进行血液，肝和肾检查，并且在检测有害物质技术人员的健康影响方面用途有限。

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