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首页> 外文期刊>Occupational and environmental medicine >Respiratory symptoms and lung function in alumina refinery employees.
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Respiratory symptoms and lung function in alumina refinery employees.

机译：氧化铝精炼厂员工的呼吸系统症状和肺功能。

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OBJECTIVES: Employees in alumina refineries are known to be exposed to a number of potential respiratory irritants, particularly caustic mist and bauxite and alumina dusts. To examine the prevalence of work related respiratory symptoms and lung function in alumina refinery employees and relate these to their jobs. METHODS: 2964 current employees of three alumina refineries in Western Australia were invited to participate in a cross sectional study, and 89% responded. Subjects were given a questionnaire on respiratory symptoms, smoking, and occupations with additional questions on temporal relations between respiratory symptoms and work. Forced expiratory volume in 1 second (FEV(1)) and forced vital capacity (FVC) were measured with a rolling seal spirometer. Atopy was assessed with prick skin tests for common allergens. Associations between work and symptoms were assessed with Cox's regression to estimate prevalence ratios, and between work and lung function with linear regression. RESULTS: Work related wheeze, chest tightness, shortness of breath, and rhinitis were reported by 5.0%, 3.5%, 2.5%, and 9.5% of participants respectively. After adjustment for age, smoking, and atopy, most groups of production employees reported a greater prevalence of work related symptoms than did office employees. After adjustment for age, smoking, height, and atopy, subjects reporting work related wheeze, chest tightness, and shortness of breath had significantly lower mean levels of FEV(1) (186, 162, and 272 ml respectively) than subjects without these symptoms. Prevalence of most work related symptoms was higher at refinery 2 than at the other two refineries, but subjects at this refinery had an adjusted mean FEV(1) >60 ml higher than the others. Significant differences in FVC and FEV(1)/FVC ratio, but not FEV(1), were found between different process groups. CONCLUSIONS: There were significant differences in work related symptoms and lung function between process groups and refineries, but these were mostly not consistent. Undefined selection factors and underlying population differences may account for some of these findings but workplace exposures may also contribute. The differences identified between groups were unlikely to be clinically of note.
机译：目标：已知氧化铝精炼厂的员工会接触到许多潜在的呼吸道刺激物，特别是苛性雾，铝土矿和氧化铝粉尘。检查氧化铝精炼厂员工与工作有关的呼吸症状和肺功能的患病率，并将其与工作相关联。方法：西澳大利亚州三家氧化铝精炼厂的2964名现任员工应邀参加了一项横断面研究，其中89％的回答。为受试者提供了有关呼吸道症状，吸烟和职业的调查表，并就呼吸道症状与工作之间的时间关系提出了其他问题。用滚动密封肺活量计测量1秒钟的强制呼气量（FEV（1））和强制肺活量（FVC）。通过点刺皮肤测试评估特应性常见过敏原。使用Cox回归评估工作和症状之间的关联以估计患病率，使用线性回归评估工作和肺功能之间的关联。结果：分别有5.0％，3.5％，2.5％和9.5％的参与者报告了与工作相关的喘息，胸闷，呼吸急促和鼻炎。在调整了年龄，吸烟和特应性疾病之后，大多数生产员工群体的工作相关症状的患病率均高于办公室员工。在调整了年龄，吸烟，身高和特应性之后，报告与工作有关的喘息，胸闷和气短的受试者的FEV（1）平均水平（分别为186、162和272 ml）显着低于没有这些症状的受试者。在炼油厂2中，大多数与工作有关的症状的患病率高于其他两个炼油厂，但是在该炼油厂中，受试者的平均FEV（1）调整后平均值高于其他炼油厂60 ml。在不同的过程组之间发现FVC和FEV（1）/ FVC比率有显着差异，但FEV（1）没有显着差异。结论：工艺组和炼油厂之间在与工作有关的症状和肺功能方面存在显着差异，但大多不一致。未确定的选择因素和潜在的人口差异可能是其中一些发现的原因，但工作场所的暴露也可能会造成这种情况。两组之间确定的差异不太可能在临床上引起注意。

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