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首页> 外文期刊>Occupational and environmental medicine >Prevention of long-term sickness absence and major depression in high-risk employees: a randomised controlled trial.
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Prevention of long-term sickness absence and major depression in high-risk employees: a randomised controlled trial.

机译:预防高风险员工长期缺勤和严重抑郁:一项随机对照试验。

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OBJECTIVES: To examine the efficacy of early intervention on the prevention of long-term sickness absence and major depression among employees at high risk of future sickness absence and with mild to severe depressive complaints. METHODS: Randomised controlled trial conducted among employees working in an office environment. 139 employees were identified both at high risk of future sickness absence and with mild to severe depressive complaints through screening. Subsequently, they were randomly assigned to the intervention group (n = 69) or the control group (n = 70). Objective sickness absence was analysed at 12 and 18 months of follow-up. Depressive complaints were assessed by the Beck Depression Inventory (BDI-II) at baseline, and at 6 and 12 months of follow-up. RESULTS: Intention-to-treat analyses showed a significant difference in total sickness absence duration between the intervention (27.5 calendar days (SD 44.7)) and control group (50.8 days (SD 75.8)) over 12 months of follow-up, a reduction of 46% (p = 0.017). The intervention group showed a non-significantly lower proportion of long-term sickness absence spells compared with the control group (p = 0.127). Statistically significant and clinically relevant differences in depressive complaints were found after both 6 months (p = 0.001) and 12 months (p = 0.005) of follow-up, in favour of the intervention group. Relative risk reductions (RRR) were 19.2% and 19.8% respectively. Sickness absence data were available for all participants over 18 months of follow-up. Questionnaire data were available for 99 (at 6 months) and 90 participants (at 12 months). No adverse events or side effects occurred. CONCLUSIONS: Early intervention in employees with mild to severe depressive complaints and high risk of future long-term sickness absence proved to be effective in preventing/reducing both sickness absence and depressive complaints.
机译:目的:研究早期干预对预防未来长期缺勤和严重抑郁症的雇员的有效性,这些雇员具有未来缺勤的高风险和轻度至重度抑郁症的抱怨。方法:在办公室环境中的员工中进行的随机对照试验。通过筛查,确定了139名有未来患病风险的员工以及患有轻度至重度抑郁症投诉的员工。随后,他们被随机分为干预组(n = 69)或对照组(n = 70)。在随访的12和18个月分析了客观疾病的缺乏。贝克抑郁量表(BDI-II)在基线以及随访6个月和12个月时评估了抑郁症的主诉。结果:意向性治疗分析显示,在随访的12个月中,干预措施(27.5历日(SD 44.7))和对照组(50.8天(SD 75.8))的总疾病缺席持续时间存在显着差异,减少了46%(p = 0.017)。与对照组相比,干预组的长期病假期间比例没有显着降低(p = 0.127)。在随访6个月(p = 0.001)和12个月(p = 0.005)后,发现抑郁症的投诉具有统计学意义和临床相关性,有利于干预组。相对风险降低(RRR)分别为19.2%和19.8%。在18个月的随访中,所有参与者均可获得疾病缺席数据。可获得99位(6个月)和90位参与者(12个月)的问卷调查数据。没有发生不良事件或副作用。结论:对患有轻度至重度抑郁症投诉以及未来长期长期缺勤的高风险员工的早期干预被证明可有效预防/减少疾病缺席和抑郁症投诉。

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