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首页> 外文期刊>Occupational and environmental medicine >Hours of work and the risk of developing impaired fasting glucose or type 2 diabetes mellitus in Japanese male office workers.
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Hours of work and the risk of developing impaired fasting glucose or type 2 diabetes mellitus in Japanese male office workers.

机译：日本男性上班族的工作时间和空腹血糖受损或2型糖尿病的风险。

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OBJECTIVE: To investigate the association between duration of overtime and the development of impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM). METHODS: A cohort of 1266 Japanese male office workers aged 35-59 years and free of IFG (fasting plasma glucose concentration 6.1-6.9 mmol/l), type 2 DM (fasting plasma glucose concentration of 7.0 mmol/l or more or taking hypoglycaemic medication), history of diabetes, or medication for hypertension were re-examined over 5 successive years after their initial examinations in 1994. RESULTS: 138 men developed IFG or type 2 DM during the 5736 person-years of follow up. After controlling for potential predictors of diabetes, the relative risks of IFG or type 2 DM, compared with those who worked <8.0 hours a day, were 0.82 (95% confidence interval (95% CI) 0.54 to 1.26), 0.69 (95% CI 0.38 to 1.26), 0.63 (95% CI: 0.37 to 1.09), and 0.50 (95% CI: 0.25 to 0.98) for those who worked 8.0-8.9, 9.0-9.9, 10.0-10.9, and of 11.0 hours or more a day, respectively (p for trend=0.020). 87 and 54 men developed IFG and type 2 DM during the 5817 and 5937 person-years of follow up, respectively. The multivariate adjusted relative risks of IFG tended to decrease with an increase in hours of overtime work a day, but did not reach significance (p for trend=0.202). On the other hand, the multivariate adjusted relative risks of type 2 DM significantly decreased with an increase in hours of overtime work a day (p for trend=0.014). CONCLUSION: Longer overtime is a negative risk factor for the development of IFG or type 2 DM in Japanese male office workers.
机译：目的：探讨加班时间与空腹血糖（IFG）或2型糖尿病（DM）受损之间的关系。方法：队列的1266名日本男性上班族，年龄在35-59岁之间，没有IFG（空腹血糖浓度为6.1-6.9 mmol / l），2型DM（空腹血糖浓度为7.0 mmol / l或更高或服用降血糖药）在1994年进行初次检查后，连续5年对糖尿病史或高血压药物进行了重新检查。结果：138名男性在5736人年的随访期间发展了IFG或2型DM。在控制了潜在的糖尿病预测因素之后，与每天工作少于8.0小时的人群相比，IFG或2型DM的相对风险分别为0.82（95％置信区间（95％CI）0.54至1.26），0.69（95％）工作时间在8.0-8.9、9.0-9.9、10.0-10.9和11.0小时或以上的人员的CI为0.38至1.26），0.63（95％CI为0.37至1.09）和0.50（95％CI为0.25至0.98）分别为一天（趋势p = 0.020）。在5817和5937人-年的随访期间，分别有87和54名男性患上了IFG和2型DM。 IFG的多变量调整相对风险倾向于随着每天加班时间的增加而降低，但并未达到显着水平（趋势p = 0.202）。另一方面，随着每天加班时间的增加，经多变量调整的2型DM相对危险度显着降低（趋势p = 0.014）。结论：长时间加班是日本男性上班族发展IFG或2型DM的负面风险因素。

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