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首页> 外文期刊>Occupational and environmental medicine >Cancer incidence among workers exposed to softwood dust in Lithuania
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Cancer incidence among workers exposed to softwood dust in Lithuania

机译：立陶宛接触软木粉尘的工人中的癌症发病率

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摘要

Objectives: The aim of this study was to assess cancer incidence in a cohort of woodworkers exposed to softwood dust in a Lithuanian wooden joinery products factory. Methods: The study population consisted of 1518 workers (1080 men and 438 women) employed in the factory for at least 1 year between 1947 and 1996 and living in Lithuania on 1 January 1978, when the follow-up for cancer incidence began. The follow-up period for cancer was 1978-2007. Cancer risk was assessed by standardised incidence ratios (SIR) with reference to the national population. Results: Overall cancer incidence was not increased among woodworkers. However, the number of mouth and pharynx cancer cases among male woodworkers was significantly increased compared with expected numbers (SIR 2.19, 95% CI 1.17 to 3.74). A higher risk was found for cancer of the buccal cavity than for pharyngeal cancer (SIRs 2.83 and 1.45, respectively). The SIR for larynx cancer was also elevated (SIR 1.39, 95% CI 0.64 to 2.64) among men, while the number of lung cancer cases was higher than expected only among women (SIR 2.07, 95% CI 00.57 to 5.31). Conclusions: This results of this study support the hypothesis that exposure to softwood dust may increase the risk of oral and pharyngeal cancer. No support was found for an increased risk of other respiratory cancers among workers exposed to softwood dust.
机译：目的：本研究的目的是评估立陶宛一家木制细木工制品厂暴露于软木粉尘的一群木工的癌症发病率。方法：研究对象包括1518名工人（1080名男性和438名女性），这些工人在1947年至1996年期间在工厂工作了至少1年，并于1978年1月1日在立陶宛生活，随后开始了癌症发病率的随访。癌症的随访期为1978-2007年。参照国家人口，通过标准化发病率（SIR）评估癌症风险。结果：木工的总体癌症发病率没有增加。但是，男性木工中的口腔癌和咽癌病例数比预期数显着增加（SIR 2.19，95％CI 1.17至3.74）。发现颊腔癌的风险高于咽癌的风险（分别为SIR 2.83和1.45）。男性的喉癌SIR也升高（SIR 1.39，95％CI 0.64至2.64），而肺癌病例数仅比女性高（SIR 2.07，95％CI 00.57至5.31）。结论：这项研究的结果支持以下假设，即接触软木粉尘可能增加口腔癌和咽癌的风险。在接触软木粉尘的工人中，没有发现增加其他呼吸道癌风险的证据。

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