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首页> 外文期刊>Occupational and environmental medicine >Allergy among veterinary medicine students in The Netherlands.
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Allergy among veterinary medicine students in The Netherlands.

机译：荷兰的兽医专业学生过敏。

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BACKGROUND: Veterinary medicine students who practice with animals are potentially exposed to many occupational agents, yet sensitisation and allergic symptoms among this group have not been studied extensively. OBJECTIVE: The objective of this study was to estimate the prevalence of sensitisation and allergic symptoms in veterinary medicine students in association with study specialisation over time. METHODS: A questionnaire-based cross-sectional study was conducted. Blood was collected and tested for total and specific serum IgE for 16 different common and study-specific allergens using enzyme immunoassay. RESULTS: New development of self-reported allergic symptoms to various allergens occurred in 8.7%, of which 44% was deducted against animals. Handling farm animals was strongly associated with self-reported allergies to various allergens (OR=6.9, 95% CI 1.9 to 25) and animal allergens (OR=12, 95% CI 1.4 to 103). Sensitisation to at least one allergen occurred in 33.1%. Sensitisation prevalence tended to be elevated in later years of the equine study program. In contrast to self-reported allergies, the prevalence of sensitisation to any allergen decreased with prolonged study duration for those specialising in farm animal health (years 3-5: OR=0.5, 95% CI 0.3 to 1.1; year 6: OR=0.2, 95% CI 0.1 to 0.5). This was independent of whether people were raised on a farm, which is in itself a protective factor for allergy and sensitisation. CONCLUSION: This study provides evidence of an elevated prevalence of allergic symptoms with increasing years of veterinary study, suggesting that contact with animals, more specifically contact to farm animals, is a risk factor for the development of symptoms.
机译：背景：与动物一起练习的兽医学学生可能会接触许多职业病，但是尚未对该人群中的致敏性和过敏性症状进行广泛研究。目的：本研究的目的是随着时间的推移，结合研究专业化程度来估计兽医学学生的致敏性和过敏症状患病率。方法：进行了基于问卷调查的横断面研究。收集血液并使用酶免疫法检测16种不同的常见和研究特异性过敏原的总血清IgE和特异性血清IgE。结果：对各种过敏原自我报告的过敏症状出现了新发展，占8.7％，其中44％是针对动物的。饲养牲畜与自我报告的对各种过敏原的过敏（OR = 6.9，95％CI 1.9至25）和动物过敏原（OR = 12，95％CI 1.4-103）密切相关。至少一种过敏原的致敏率为33.1％。在马研究计划的后期，过敏症的患病率倾向于升高。与自我报告的过敏相反，对农场动物健康专门研究者，对任何过敏原的致敏率随研究时间的延长而降低（3-5年：OR = 0.5，95％CI 0.3到1.1; 6年：OR = 0.2 ，95％CI 0.1至0.5）。这与人们是否在农场长大无关，这本身就是过敏和致敏的保护因素。结论：这项研究提供了随着兽医研究年限的增加，过敏性症状患病率升高的证据，这表明与动物的接触，尤其是与家畜的接触，是发生症状的危险因素。

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