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A pheochromocytoma case in a 6 - year - old sheep

机译:6岁绵羊的嗜铬细胞瘤病例。

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Pheochromocytomas, rare in all species except rats, dogs and cattle, are neuroendocrine tumours of adrenal chromaffin cells. This case reports the occurrence of a tan-coloured mass in medulla of the left adrenal gland in a 6 - year - old female sheepdead from pneumonia. Histopathologically, the tumour was composed by pleomorphic cells with marked nuclei and abundant eosinophil cytoplasm. Immunohistochemistry evidenced expression of neuron specific enolase (NSE) and S100 protein in neoplastic cells associated with a strong Ki-67 activity. This tumour was diagnosed as pheochromocytoma. This is the first report of a pheochromocytoma in a sheep.
机译:嗜铬细胞瘤是肾上腺嗜铬细胞的神经内分泌肿瘤,除大鼠,狗和牛外在所有物种中均很少见。该病例报告了一名六岁的肺炎女死者在左肾上腺的髓质中出现了棕褐色的肿块。在组织病理学上,肿瘤由具有明显核和丰富嗜酸性粒细胞胞质的多形细胞组成。免疫组织化学证实神经元特异性烯醇酶(NSE)和S100蛋白在与强Ki-67活性相关的赘生性细胞中表达。该肿瘤被诊断为嗜铬细胞瘤。这是绵羊嗜铬细胞瘤的首次报道。

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