...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Reproductive toxicology >Association between maternal blood cadmium during pregnancy and birth weight and the risk of fetal growth restriction: The EDEN mother-child cohort study
【24h】

Association between maternal blood cadmium during pregnancy and birth weight and the risk of fetal growth restriction: The EDEN mother-child cohort study

机译：孕期孕妇血镉与出生体重和胎儿生长受限风险之间的关联：EDEN母婴队列研究

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The objective of this study is to investigate the potential effect of maternal environmental cadmium (Cd) exposure on birth weight and fetal growth restriction (FGR). A total of 901 pregnant women from the EDEN cohort study were enrolled from two maternity units. Blood Cd was measured at mid-pregnancy and associations with birth weight and FGR were analyzed. Maternal Cd levels were associated with reduced birth weight in the offspring of women who smoked during pregnancy (b= -113.7; p= 0.001). Smoking during pregnancy and maternal blood Cd concentrations had comparable effects on FGR incidence (OR 1.89; 95% CI: 1.00-3.58 and OR = 1.41; 95% CI: 1.00-1.99, respectively). This study highlights the effect of Cd toxicity on fetal growth through the probable accumulation and transmission of this metal through the placenta. The close relationship between blood Cd levels and smoking habits indicates that Cd may be a relevant biomarker for smoking toxicity on fetal development.
机译：这项研究的目的是调查母体环境镉（Cd）暴露对出生体重和胎儿生长限制（FGR）的潜在影响。来自EDEN队列研究的901名孕妇来自两个产科。在怀孕中期测量血液中的镉，并分析其与出生体重和FGR的相关性。在怀孕期间吸烟的妇女的后代中，母亲的镉水平与出生体重的降低有关（b = -113.7; p = 0.001）。怀孕期间吸烟和孕妇血液中Cd浓度对FGR发生率具有可比的影响（OR分别为1.89; 95％CI：1.00-3.58; OR = 1.41; 95％CI：1.00-1.99）。这项研究强调了镉毒性通过这种金属可能通过胎盘的积累和传播而对胎儿生长的影响。血液中镉含量与吸烟习惯之间的密切关系表明，镉可能是吸烟对胎儿发育毒性的相关生物标志物。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号