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首页> 外文期刊>Onkologie >Outcome of early breast cancer treated in an urban and a rural breast cancer unit in Germany
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Outcome of early breast cancer treated in an urban and a rural breast cancer unit in Germany

机译：德国城市和农村乳腺癌部门治疗早期乳腺癌的结果

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Background: Conflicting evidence has been published concerning survival disadvantages in the outcome of breast cancer patients in relationship to their residency in urban or rural communities. Methods: The primary aim of this study was to evaluate differences in patients and treatment characteristics between an urban and a rural breast cancer unit. Therefore, all early breast cancer patients treated consecutively between 1999 and 2007 in a rural and an urban breast cancer unit were included. Patient and tumor characteristics, treatment strategies, and guideline adherence were included to evaluate the prognoses of both populations. Results: Overall, data from 2,566 patients were included in this analysis. The 610 patients treated in the rural unit showed significantly more negative prognostic criteria than the 1,956 patients treated in the urban center. No differences were observed with respect to surgical and systemic treatment after adjustment for prognostic parameters. Adherence to national guidelines did not differ significantly between both settings and ranged between 78.0 and 95.6%. Furthermore, no differences regarding recurrence-free and overall survival were observed. Conclusions: The stage-adjusted pattern of care was similar in 2 German breast care units in a rural region and an urban area. Nevertheless, an earlier diagnosis of breast cancer should be enforced in rural areas to avoid extended treatment burden.
机译：背景：关于乳腺癌患者预后的生存劣势与其在城市或农村社区中的居住状况有关的证据已被发表。方法：本研究的主要目的是评估城市和农村乳腺癌单位之间患者和治疗特征的差异。因此，纳入了1999年至2007年间在农村和城市乳腺癌部门连续接受治疗的所有早期乳腺癌患者。包括患者和肿瘤特征，治疗策略和指南依从性，以评估两个人群的预后。结果：总体而言，该分析纳入了2566名患者的数据。农村地区接受治疗的610例患者的预后判断标准明显高于城市中心接受治疗的1,956例患者。调整预后参数后，在外科手术和全身治疗方面未观察到差异。两种情况下遵守国家准则的差异均不显着，介于78.0％至95.6％之间。此外，未观察到无复发生存期和总生存期的差异。结论：分阶段调整的护理模式在农村地区和城市地区的两个德国乳房护理单位中相似。尽管如此，应该在农村地区对乳腺癌进行早期诊断，以免延长治疗负担。

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