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首页> 外文期刊>Oncologie. >Concomitant chemoradiation for locally advanced non-small cell lung cancer [Chimioradiothérapie concomitante pour le traitement des cancers bronchiques non à petites cellules, localisés au thorax, inopérables ou non résécables]
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Concomitant chemoradiation for locally advanced non-small cell lung cancer [Chimioradiothérapie concomitante pour le traitement des cancers bronchiques non à petites cellules, localisés au thorax, inopérables ou non résécables]

机译:局部晚期非小细胞肺癌的化学放疗[局部放疗,不能手术或不能切除的非小细胞肺癌的同期放化疗]

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摘要

Concomitant chemoradiation is the standard strategy for unresectable locally advanced non-small cell lung cancer (NSCLC). Its modalities used currently include three-dimensional conformal techniques, allowing dose escalation and sequential and concurrent combination with new generation cytotoxic agents. Phase III trials have not demonstrated any benefit from induction and consolidation chemotherapy in this setting. New techniques of radiation may also increase the efficacy and the feasibility of radiation. The integration of targeted therapies in the management of stage III NSCLC is also under investigation. This constant progress makes chemoradiation one of the most promising combined treatments in thoracic oncology.
机译:伴随化学放疗是不可切除的局部晚期非小细胞肺癌(NSCLC)的标准策略。目前,其使用的方法包括三维共形技术,可以逐步提高剂量,并与新一代细胞毒剂相继并发结合使用。在这种情况下,III期临床试验尚未显示出从诱导和巩固化疗中获益。辐射的新技术还可以提高辐射的效力和可行性。还正在研究将靶向疗法整合到III期NSCLC的管理中。这种不断的进步使化学放射疗法成为胸肿瘤学中最有前途的联合疗法之一。

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