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首页> 外文期刊>Oncology >Tumor biology trumps anatomy in breast cancer brain metastases.
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Tumor biology trumps anatomy in breast cancer brain metastases.

机译:肿瘤生物学在乳腺癌脑转移中胜过解剖学。

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摘要

In this issue of ONCOLOGY, Drs. Lim and Lin present a comprehensive and up-to-date review of the basic biology of breast cancer brain metastasis (BCBM) and of emerging strategies for treating this increasingly common complication of advanced breast cancer (BC) (BC is second only to non-small-cell lung cancer in the frequency of central nervous system [CNS] metastasis.) It is clear that as the efficacy of treatments for extracranial metastatic BC have improved over time, CNS metastases have increasingly been exposed as a vulnerability, with the CNS indeed a sanctuary site; they necessitate directed (often multidisciplinary) therapeutic approaches requiring special expertise (ideally via an experienced interdisciplinary team).
机译:在本期《肿瘤学》中,Dr。林(Lim)和林(Lin)对乳腺癌脑转移(BCBM)的基本生物学以及用于治疗这种日益常见的晚期乳腺癌(BC)并发症的新兴策略进行了全面,最新的综述(BC仅次于非乳腺癌显然,随着颅外转移性BC治疗的效果随着时间的推移而提高,CNS转移越来越容易被暴露为一种脆弱性,而CNS确实避难所;他们需要直接(通常是多学科)的治疗方法,需要特殊的专业知识(最好是通过经验丰富的跨学科团队)。

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