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Radium-223 vs EBRT for multiple painful bone metastases: The data favor radium-223

机译:Radium-223 vs EBRT可治疗多种疼痛的骨转移:数据偏向镭223

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Over 90% of patients with metastatic prostate cancer have bone metastases, and the vast majority of these patients develop bone pain from the metastases during the course of the disease. [ 1 ] All such patients should be treated with zoledron- ic acid and/or denosumab.[2] The disease course of prostate cancer can often be very protracted, with survival ranging from several years to decades. During that time, the bone marrow often becomes infiltrated by the cancer, leading to anemia and thrombocytopenia. Patients commonly need red cell transfusions during the terminal phases of the disease. Moreover, at least two chemotherapy agents that can suppress bone marrow function-docetaxel and cabazitaxel-should be used to extend life and improve quality of life. [3]
机译:超过90%的转移性前列腺癌患者有骨转移,这些患者中的绝大多数在疾病过程中因转移而发展为骨痛。 [1]所有此类患者均应接受唑来膦酸和/或地诺单抗治疗。[2]前列腺癌的病程通常很漫长,生存期从数年到数十年不等。在这段时间里,骨髓经常被癌症浸润,导致贫血和血小板减少。患者通常在疾病末期需要输注红细胞。此外,应该使用至少两种可以抑制骨髓功能的化疗药物多西他赛和卡巴他赛来延长生命和改善生活质量。 [3]

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    《Oncology》 |2014年第4期|共2页
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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 肿瘤学;
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