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首页> 外文期刊>Oncology letters >Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma
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Hemithyroidectomy increases the risk of disease recurrence in patients with ipsilateral multifocal papillary thyroid carcinoma

机译：甲状腺切除术增加同侧多灶性甲状腺乳头状癌患者疾病复发的风险

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摘要

Papillary thyroid carcinoma (PTC) is often clinically multifocal. In this study, the clinicopathological characteristics of a total of 347 PTC patients treated between 2006 and 2007 were investigated in order to assess the risk factors for tumor recurrence in patients with multifocal PTC. Of all the PTC cases reviewed, 35 (10%) were categorized as multifocal PTC. Patients with multifocal PTC were significantly more likely to have extrathyroidal extension, lymph node metastases and disease recurrence (P<0.05). Hemithyroidectomy resulted in a significantly higher incidence of tumor recurrence in patients with ipsilateral multifocal PTC compared with unifocal PTC patients (P<0.01). In conclusion, hemithyroidectomy was associated with tumor recurrence in patients with ipsilateral multifocal PTC but not those with unifocal PTC. Hemithyroidectomy should only be carried out after careful deliberation when involving patients with ipsilateral multifocal PTC.
机译：甲状腺乳头状癌（PTC）在临床上通常是多灶性的。在这项研究中，调查了2006年至2007年间共347例PTC患者的临床病理特征，以评估多灶PTC患者肿瘤复发的危险因素。在所审查的所有PTC案例中，有35例（10％）被归类为多焦点PTC。患有多灶性PTC的患者更有可能出现甲状腺外扩张，淋巴结转移和疾病复发（P <0.05）。与单焦点PTC患者相比，半甲状腺切除术导致同侧多焦点PTC患者的肿瘤复发率显着更高（P <0.01）。总之，在同侧多灶性PTC患者中，半甲状腺切除术与肿瘤复发相关，而在单灶性PTC中则不相关。当涉及同侧多灶性PTC患者时，仅应在仔细考虑后才进行甲状腺甲状腺切除术。

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