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首页> 外文期刊>Ophthalmologica: International Journal of Ophthalmology=Journal International d'Ophtalmologie >Comparison of clinical outcomes between 'on-flap' and 'off-flap' epi-LASIK for myopia: a meta-analysis.
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Comparison of clinical outcomes between 'on-flap' and 'off-flap' epi-LASIK for myopia: a meta-analysis.

机译：近视眼“上皮瓣”和“下皮瓣” epi-LASIK的临床结果比较：一项荟萃分析。

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OBJECTIVE: To examine possible differences in clinical outcomes between off-flap and on-flap epipolis laser in situ keratomileusis (epi-LASIK) for myopia. METHODS: Pertinent studies were selected by extensive searches. A total of 9 studies reporting on a total of 958 eyes were included in the present meta-analysis. Statistical analysis was performed using RevMan 5.0 software. RESULTS: There were no significant differences in the final refractive spherical equivalent (p = 0.38), manifest refractive spherical equivalent within +/-0.50 D of the target (p = 0.76), final uncorrected visual acuity (p = 0.90), loss of >/=1 line of best spectacle-corrected visual acuity (p = 0.99), and corneal haze at 3 months postoperatively (p = 0.96) or more than 6 months (p = 0.64). More patients felt severe pain in the on-flap group than in the off-flap group, although this finding was not statistically significant (p = 0.05). However, off-flap epi-LASIK had a better mean uncorrected visual acuity at 3 days (p = 0.04) and 5 days (p = 0.01), and faster re-epithelialization (p < 0.00001) after surgery. CONCLUSIONS: According to the available data, off-flap and on-flap epi-LASIK had equal visual and refractive outcomes for the treatment of myopia. Off-flap epi-LASIK had more rapid re-epithelialization and visual recovery compared to on-flap epi-LASIK.
机译：目的：探讨近视眼皮瓣和皮瓣上原位角膜磨镶术（epi-LASIK）之间临床结果的可能差异。方法：通过广泛搜索选择相关研究。本荟萃分析共纳入9项研究，报告共958眼。使用RevMan 5.0软件进行统计分析。结果：最终屈光度当量（p = 0.38），目标屈光度在+/- 0.50 D以内（p = 0.76），最终未矫正视力（p = 0.90），视力丧失均无显着差异。 > / = 1最佳眼镜矫正视力线（p = 0.99），以及术后3个月（p = 0.96）或超过6个月（p = 0.64）的角膜混浊。尽管没有发现统计学意义上的显着性差异，但皮瓣上组比皮瓣上组有更多的患者感到严重疼痛（p = 0.05）。然而，皮瓣外表LASIK在手术后3天（p = 0.04）和5天（p = 0.01）时具有更好的平均未矫正视敏度，并且术后再上皮化更快（p <0.00001）。结论：根据现有数据，皮瓣近视和皮瓣近视治疗近视的视觉和屈光效果均相同。与瓣上Epi-LASIK相比，瓣上Epi-LASIK具有更快的重新上皮形成和视觉恢复。

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