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首页> 外文期刊>Ophthalmology >Spectrum of CD30+ lymphoid proliferations in the eyelid lymphomatoid papulosis, cutaneous anaplastic large cell lymphoma, and anaplastic large cell lymphoma.
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Spectrum of CD30+ lymphoid proliferations in the eyelid lymphomatoid papulosis, cutaneous anaplastic large cell lymphoma, and anaplastic large cell lymphoma.

机译：CD30 +淋巴样增生在眼睑淋巴瘤样丘疹，皮肤间变性大细胞淋巴瘤和间变性大细胞淋巴瘤中的增殖谱。

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摘要

PURPOSE: To report the clinicopathologic features of 3 patients with CD30(+) lymphoid proliferations of the eyelid. DESIGN: Retrospective case series. PARTICIPANTS: Patients with cutaneous CD30(+) lymphoproliferative lesions of the eyelid. METHODS: Three patients with CD30(+) non-mycosis fungoides T-cell lymphoid infiltrates of the eyelid were identified. The histories, clinical findings, pathologic features including immunohistochemical staining, treatments, and outcomes were reviewed and compared. MAIN OUTCOME MEASURES: Pathologic findings including immunohistochemical analysis. RESULTS: The patients included an 81-year-old man, an 18-year-old man, and a 42-year-old woman with CD30(+) lymphoid proliferations of the eyelid and adjacent soft tissue. The first patient had an isolated crateriform eyelid lesion that was classified as lymphomatoid papulosis (LyP). The second patient had an isolated multinodular lesion of the eyelid that was classified as cutaneous anaplastic large cell lymphoma (cALCL). The third patient presented with eyelid edema with an underlying mass and was found to have widely disseminated anaplastic large cell lymphoma (ALCL). Diagnoses were dependent on clinical findings. CONCLUSIONS: The CD30(+) lymphoid proliferations represent a spectrum of conditions ranging from indolent LyP, to moderately aggressive cALCL, to highly aggressive ALCL. Interpretation of the pathologic findings in CD30(+) lymphoid proliferations is based in part on clinical findings. FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any material discussed in this article.
机译：目的：报告3例眼睑CD30（+）淋巴样增生患者的临床病理特征。设计：回顾案系列。参与者：眼睑皮肤CD30（+）淋巴增生性皮肤病变的患者。方法：确定了3例眼睑CD30（+）非真菌病真菌T细胞淋巴样浸润患者。回顾并比较了病史，临床表现，包括免疫组织化学染色在内的病理特征，治疗方法和结果。主要观察指标：病理结果包括免疫组化分析。结果：患者包括一个81岁的男性，一个18岁的男性和一个42岁的女性，其眼睑和邻近软组织的CD30（+）淋巴样增生。第一名患者患有孤立的颅状眼睑病变，被分类为淋巴瘤样丘疹（LyP）。第二名患者患有孤立的眼睑多结节病变，被分类为皮肤间变性大细胞淋巴瘤（cALCL）。第三例患者出现眼睑水肿并伴有潜在肿物，被发现广泛分布于间变性大细胞淋巴瘤（ALCL）。诊断取决于临床发现。结论：CD30（+）淋巴样增生代表一系列疾病，范围从惰性LyP，中度侵袭性cALCL到高度侵袭性ALCL。 CD30（+）淋巴样增生的病理结果的解释部分基于临床发现。财务披露：作者对本文讨论的任何材料均没有所有权或商业利益。

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