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首页> 外文期刊>Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA >Reference charts for the relationships between dual-energy X-ray absorptiometry-assessed bone mineral content and lean mass in 3,063 healthy men and premenopausal and postmenopausal women.
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Reference charts for the relationships between dual-energy X-ray absorptiometry-assessed bone mineral content and lean mass in 3,063 healthy men and premenopausal and postmenopausal women.

机译：3060名健康男性和绝经前和绝经后女性经双能X线骨密度仪评估的骨矿物质含量与瘦体重之间关系的参考图表。

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Correlations between dual-energy X-ray absorptiometry (DXA)-assessed bone mineral content and lean mass (BMC-LM curves), and between BMC/LM ratio and age ([BMC/LM]-age curves), were analyzed in the whole body (WB), the upper limbs (ULs) and the lower limbs (LLs) of 3,063 healthy Hispanic adults. Groups of 472 men aged 25-87 years, 1,035 premenopausal (pre-MP) women aged 27-54 years, and 1,556 post-menopausal (post-MP) women aged 48-93 years were studied with a GE-Lunar DPX-Plus device. BMC-LM curves confirmed previous observations that BMC and LM masses always correlate linearly, with similar slopes within each region, but differing in intercepts according to gender and hormonal status. Multiple regression tests showed little or no independent interaction of body weight or height with those relationships. [BMC/LM]-age curves were flat in men but showed the positive influence of estrogens throughout the age range in women. Z-scored graphs of all the corresponding relationships were compiled, showing theconfidence intervals for means +/-1, +/-2, and +/-3 SDs of the data (+/-1, +/-2, +/-3 z-scores) along BMC-LM and [BMC/LM]-age curves. These charts are proposed as references for assessing how well bone mass (as assessed by BMC) and muscle mass (assumed proportional to LM) follow the natural anthropometric/biomechanical proportionality in Hispanic men and women within the age range studied, employing similar devices. Charts for LLs, showing the lowest variance amongst the studied correlations and approaching the origin as an exclusive feature, could provide the most accurate reference curves. Differences between data from ULs and LLs may provide information about any eventual interaction of body-weight bearing with the general results. The proposed analysis may provide useful information for approaching a differential diagnosis between disuse-related and other types of osteopenias employing only DXA.
机译：在双能X线骨密度仪（DXA）评估的骨矿物质含量和瘦体重（BMC-LM曲线）之间以及BMC / LM比与年龄（[BMC / LM]-年龄曲线）之间的相关性进行了分析。 3,063名健康的西班牙裔成年人的全身（WB），上肢（UL）和下肢（LL）。使用GE-Lunar DPX-Plus对年龄在25-87岁的472名男性，年龄在27-54岁的1,035名绝经前（MP之前）女性和48-93岁的1,556名绝经后（MP后）女性进行了研究。设备。 BMC-LM曲线证实了先前的观察结果，即BMC和LM质量始终线性相关，每个区域内的斜率相似，但根据性别和荷尔蒙状态，截距不同。多元回归测试显示，体重或身高与这些关系很少或没有独立的相互作用。 [BMC / LM]-年龄曲线在男性中是平坦的，但在整个年龄范围内均显示雌激素的积极影响。编制所有对应关系的Z评分图，显示数据的均值+/- 1，+ /-2和+/- 3 SD的置信区间（+/- 1，+ /-2，+ /-沿BMC-LM和[BMC / LM]-年龄曲线的3个z得分。建议使用这些图表作为参考，以评估在研究年龄范围内的西班牙裔男性和女性，使用类似的设备，骨骼质量（通过BMC评估）和肌肉质量（假设与LM成比例）遵循自然人体测量/生物力学比例的情况。 LL的图表显示了所研究的相关性之间的最低方差，并且以其独有特征接近原点，可以提供最准确的参考曲线。来自UL和LL的数据之间的差异可能会提供有关体重与最终结果之间任何最终相互作用的信息。所提出的分析可提供有用的信息，以用于仅使用DXA的与废料相关的骨质减少和其他类型的骨质减少之间的鉴别诊断。

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