...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sarcoidosis, vasculitis, and diffuse lung diseases: official journal of WASOG >Respiratory system involvement in ANCA-associated systemic vasculitides.
【24h】

Respiratory system involvement in ANCA-associated systemic vasculitides.

机译：呼吸系统参与ANCA相关的全身性血管炎。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND AND AIM OF THE WORK: The respiratory system may be involved in all systemic vasculitides (SV), although with a variable frequency. Lung disease is a very common and important feature of the antineutrophil cytoplasmic antibodies (ANCA)-associated SV (AASV), such as Wegener's granulomatosis (WG), Churg-Strauss syndrome (CSS), and microscopic polyangiitis (MPA). The aim of the work is to review the clinical findings, as well as the radiological and pathological features of respiratory system involvement in AASV. METHODS: A detailed search via the PubMed index from the National Library of Medicine, covering the period from 1980 to December 2004, was accomplished. RESULTS: In WG, almost all patients have either upper airway or lower respiratory tract disease. Solitary or multiple nodules and masses are the most common findings on chest radiograph. Asthma is a main symptom of CSS, often preceded by allergic rhinitis, frequently complicated by nasal polyposis and sinusitis. Pulmonary transient and patchy alveolar infiltrates are the most common radiographic findings. In MPA, diffuse alveolar haemorrhage (DAH) due to alveolar capillaritis is the most frequent manifestation of the respiratory involvement, clinically expressing with haemoptysis, respiratory distress and anaemia. CONCLUSIONS: The involvement of the respiratory system is a very common and important feature of AASV. There is substantial overlap in many of the clinical pulmonary features of AASV. In some cases, distinguishing between these diseases on the basis of the clinical features alone is difficult and pathological assessment is needed.
机译：工作背景和目的：尽管频率可变，但呼吸系统可能参与所有系统性血管炎（SV）。肺疾病是抗中性粒细胞胞浆抗体（ANCA）相关的SV（AASV）的非常普遍且重要的特征，例如韦格纳肉芽肿（WG），Churg-Strauss综合征（CSS）和显微多血管炎（MPA）。这项工作的目的是回顾临床发现，以及呼吸系统参与AASV的放射学和病理学特征。方法：通过国立医学图书馆的PubMed索引，进行了1980年至2004年12月的详细搜索。结果：在WG中，几乎所有患者都患有上呼吸道疾病或下呼吸道疾病。单发或多发结节和肿块是胸部X光片上最常见的发现。哮喘是CSS的主要症状，通常先于过敏性鼻炎，并发并发鼻息肉和鼻窦炎。肺部短暂性和片状肺泡浸润是最常见的影像学表现。在MPA中，由于肺泡毛细血管炎引起的弥漫性肺泡出血（DAH）是呼吸受累的最常见表现，临床上表现为咯血，呼吸窘迫和贫血。结论：呼吸系统受累是AASV的一个非常普遍且重要的特征。 AASV的许多临床肺部特征存在实质性重叠。在某些情况下，仅凭临床特征来区分这些疾病是困难的，需要进行病理评估。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号