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首页> 外文期刊>Schizophrenia research and treatment >Arousal Predisposition as a Vulnerability Indicator for Psychosis: A General Population Online Stress Induction Study
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Arousal Predisposition as a Vulnerability Indicator for Psychosis: A General Population Online Stress Induction Study

机译：易感人群易感性指标：一般人群在线压力诱导研究

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Explanatory models ascribe to arousability a central role for the development of psychotic symptoms. Thus, a disposition to hyperarousal (i.e., increased arousal predisposition (AP)) may serve as an underlying vulnerability indicator for psychosis by interacting with stressors to cause symptoms. In this case, AP, stress-response, and psychotic symptoms should be linked before the development of a diagnosable psychotic disorder. We conducted a cross-sectional online study in a population sample (N = 104; M_aga = 27.7 years, SD = 11.2, range 18-70). Participants rated their AP and subclinical psychotic symptoms. Participants reported their stress-levels before and after two stress inductions including an arithmetic and a social stressor. The participants with an increased AP generally felt more stressed. However, AP was not associated with the specific stress-response. As expected, positive psychotic symptoms were significantly associated with AP, but this was not mediated by general stress-levels. Its association to subtle, nondinical psychotic symptoms supports our assumption that AP could be a vulnerability indicator for psychosis. The trait is easily accessible via a short self-report and could facilitate the identification of people at risk and be a promising target for early stress-management. Further research is needed to clarify its predictive value for stress-responses.
机译：解释性模型将可唤醒性归因于精神病症状发展的核心作用。因此，通过与压力源相互作用以引起症状，过度兴奋的倾向（即，增加的唤醒倾向（AP））可以作为精神病的潜在脆弱性指标。在这种情况下，AP，压力反应和精神病性症状应在可诊断的精神病性疾病发展之前联系起来。我们在人群样本中进行了横断面在线研究（N = 104; M_aga = 27.7岁，SD = 11.2，范围18-70）。参与者对他们的AP和亚临床精神病症状进行了评分。参与者报告了两次压力诱导前后的压力水平，包括算术压力和社会压力。 AP增高的参与者通常感到压力更大。但是，AP与特定的压力反应无关。正如预期的那样，积极的精神病症状与AP显着相关，但这不是由一般压力水平介导的。它与微妙的，非常规的精神病症状的关联支持了我们的假设，即AP可能是精神病的脆弱性指标。通过简短的自我报告可以很容易地获得该特征，并且可以帮助识别高危人群，并成为早期压力管理的有希望的目标。需要进一步的研究来阐明其对压力反应的预测价值。

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