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首页> 外文期刊>Scandinavian journal of urology >Psychometric testing of the Norwegian version of the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26)
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Psychometric testing of the Norwegian version of the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26)

机译：挪威版《前列腺癌综合指数》复合项目（26个项目）的心理测量测试（EPIC-26）

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Objectives: In patients with prostate cancer, evaluation of quality of care requires the inclusion of patient-reported outcomes measures assessed by validated and reliable instruments. Basic psychometric tests of the Norwegian version of the Expanded Prostate Cancer Index Composite with 26 items (EPIC-26) were performed in this study. Material and methods: Translation of the original questionnaire (University of California, Los Angeles Prostate Cancer Index Composite), field testing and retranslation were done according to published guidelines. The final EPIC-26 items were subsequently selected from the Norwegian version of the EPIC-50 with slight verbal adjustments to comply with the English version of the EPIC-26. Reliability and validity were tested among 471 patients who, between 2009 and 2010, had been included in a prospective Norwegian multicenter study assessing adverse effects after radical prostatectomy or prostatic radiotherapy, usually combined with (neo)adjuvant hormone treatment. All patients completed the EPIC-26 before treatment and 3 and 12 months afterwards. Results: Internal consistency was documented by Cronbach's alpha coefficients ranging from 0.64 to 0.91 for the five domains/subdomains. Item-to-scale correlation coefficients ranged from 0.20 to 0.88, with the lowest value (0.20) for overall sexual problem. Criterion validity was proven by significant correlations between individual responses to the International Prostate Symptom Score and sum scores of the irritative/obstructive subdomain score of the EPIC-26. Satisfactory sensitivity and responsiveness reflected clinical utility for assessing between-group differences and treatment-related changes. Conclusions: Based on basic psychometric tests, the Norwegian version of the EPIC-26 showed acceptable reliability and validity for assessment of adverse effects after treatment of non-metastatic prostate cancer.
机译：目标：在前列腺癌患者中，对护理质量的评估要求包括通过有效可靠的仪器评估的患者报告的结局指标。在这项研究中，对挪威版本的扩展前列腺癌指数复合材料（26个项目）（EPIC-26）进行了基本的心理测验。材料和方法：根据已发布的指南进行原始调查表（加利福尼亚大学洛杉矶分校前列腺癌指数合成）的翻译，现场测试和重新翻译。随后从挪威版本的EPIC-50中选择了最终的EPIC-26项目，并进行了少许口头调整，以符合EPIC-26的英语版本。在2009年至2010年之间对471位患者进行了信度和效度测试，该患者已纳入一项前瞻性挪威多中心研究，评估了前列腺癌根治术或前列腺放疗后通常联合（新）辅助激素治疗后的不良反应。所有患者在治疗前以及治疗后3和12个月均完成了EPIC-26。结果：内部一致性由五个域/子域的Cronbachα系数记录，范围为0.64至0.91。项目与规模的相关系数范围从0.20到0.88，对于整体性问题而言，最低值（0.20）。个体对国际前列腺症状评分的反应与EPIC-26刺激性/阻塞性亚域评分总和之间的显着相关性证明了标准的有效性。令人满意的敏感性和反应性反映了评估组间差异和治疗相关变化的临床效用。结论：基于基本的心理测验，挪威版本的EPIC-26在评估非转移性前列腺癌治疗后的不良反应方面显示出可接受的可靠性和有效性。

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