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首页> 外文期刊>Sarcoidosis, vasculitis, and diffuse lung diseases: official journal of WASOG >Idiopathic bronchiolitis mimicking diffuse panbronchiolitis.
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Idiopathic bronchiolitis mimicking diffuse panbronchiolitis.

机译：模仿弥漫性全细支气管炎的特发性细支气管炎。

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摘要

Diffuse panbronchiolitis (DPB) is a distinct sinobronchial syndrome which has been almost exclusively reported in East Asia; only a few cases have been observed in non-Asians so far. Since 1990, when one of us described the first European case, we have screened all patients presenting with a clinical, physiopathological and radiological pattern compatible with DPB, in order to assess if the paucity of proven cases in Europe could reflect a lack of awareness of this disease among both pulmonologists and pathologists. Over a 10-years period we identified four additional DPBs, but also interestingly observed five cases of "idiopathic" bronchiolitis (IB) that had both clinical symptoms and high-resolution computed tomography (HRCT) findings indistinguishable from those of DPB, but did not show the typical histological changes. All these patients were Caucasians and presented with dyspnea, productive cough, an obstructive or mixed impairment on pulmonary function tests and chest HRCT features strongly suggesting a grade II to IV DPB. We suggest that diseases classified as IB in this study might be homogeneous entities which are clinically and radiologically similar to DPB.
机译：弥漫性全细支气管炎（DPB）是一种独特的鼻支气管综合症，在东亚几乎只有该病的报道。迄今为止，在非亚洲人中仅观察到了少数病例。自1990年以来，当我们中的一个描述第一例欧洲病例时，我们对所有表现出与DPB相容的临床，生理病理和放射学特征的患者进行了筛查，以评估欧洲已证实病例的缺乏是否可以反映出对肺病学家和病理学家中都患有这种疾病。在10年的时间里，我们发现了另外四个DPB，但有趣地还观察到了5例“特发性”毛细支气管炎（IB），其临床症状和高分辨率计算机断层扫描（HRCT）的发现与DPB的区别不明显，但没有显示典型的组织学变化。所有这些患者均为高加索人，表现为呼吸困难，生产性咳嗽，肺功能检查受阻或混合障碍以及胸部HRCT特征强烈提示II至IV级DPB。我们建议在本研究中被分类为IB的疾病可能是同质实体，在临床和放射学上与DPB相似。

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