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Laryngeal and vocal evaluation in untreated growth hormone deficient adults.

机译:未经治疗的生长激素缺乏成人的喉和声带评估。

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摘要

OBJECTIVE: To evaluate the consequences of lifetime, severe and untreated isolated growth hormone deficiency (IGHD) on vocal and laryngeal function. STUDY DESIGN: Cross-sectional. SUBJECTS AND METHODS: A total of 23 IGHD adult subjects and 22 controls were administered a questionnaire about vocal complaints and harmful voice habits, and underwent videolaryngostroboscopic examination, voice evaluation by perceptual-auditory analysis with GRBAS scale including grade of dysphonia, roughness, breathiness, asthenia and strain items, objective voice evaluation by maximum phonation time (MPT), and acoustic analysis. RESULTS: There was no difference in vocal complaints between IGHD subjects and controls. Vocal abuse and smoking were more frequent in IGHD subjects. IGHD subjects presented higher values for roughness, breathiness, and strain. Laryngopharyngeal reflux (LPR) signs and laryngeal constriction were more frequent in IGHD individuals. MPT was similar in the two groups. Fundamental frequency was higher in IGHD females and males. Harmonic to noise ratio was higher in IGHD in both genders and shimmer was lower in IGHD females. CONCLUSIONS: IGHD subjects have higher prevalence of signs of LPR and laryngeal constriction, with high pitch in both genders, which suggests a prominent role of IGHD on these parameters.
机译:目的:评估终生,严重和未经治疗的孤立生长激素缺乏症(IGHD)对人声和喉功能的影响。研究设计:横截面。受试者与方法:共向23名IGHD成人受试者和22名对照进行了有关声音主诉和有害语音习惯的问卷调查,并进行了电视喉镜检查,通过GRBAS量表通过听觉-听觉分析进行语音评估,包括听觉困难程度,粗糙度,呼吸,衰弱和紧张项目,通过最大发声时间(MPT)进行客观语音评估以及声学分析。结果:IGHD受试者和对照组之间的声音主诉没有差异。在IGHD受试者中,声音滥用和吸烟更为频繁。 IGHD受试者呈现出更高的粗糙度,呼吸性和劳损值。在IGHD患者中,喉咽反流(LPR)征象和喉缩狭窄更为常见。两组的MPT相似。 IGHD女性和男性的基本频率较高。男女中IGHD的谐波噪声比均较高,而女性中闪闪性较低。结论:IGHD受试者的LPR和喉咙收缩征象患病率较高,男女之间音调均较高,这表明IGHD在这些参数上具有重要作用。

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