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首页> 外文期刊>Scandinavian journal of primary health care. >Clinical course of suspected viral sore throat in young adults: cohort study.
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Clinical course of suspected viral sore throat in young adults: cohort study.

机译：年轻人可疑病毒性喉咙的临床病程：队列研究。

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OBJECTIVE: To evaluate the natural clinical course of suspected viral sore throat. DESIGN: Prospective cohort study. SETTING: Five military camps in Norway. METHODS: In a randomized placebo-controlled trial comparing the effect of bovine colostrum tablets or placebo on non-streptococcal sore throat in young adults no statistically significant difference in illness duration was found. The participants were thus regarded as one cohort. The authors analysed 10.0 cm visual analogue scales (VAS) scores for 'sickness' and sore throat, using 1.0 cm as a cut-off for recovery. They furthermore explored whether the VAS for sore throat was a good test to discriminate between recoveredot recovered by use of a receiver operating characteristic (ROC) curve. RESULTS: For sore throat, it was found that 51% had recovered by day 6 and 91% had recovered by day 8. Similarly for sickness, 65% had recovered by day 6 and 94% by day 8. The daily VAS scores for 'sickness' and sore throat were highly correlated (p 0.001). Themean day of recovery from 'sickness' and sore throats (based on VAS scores) was 5.5 and 4.7 respectively and 5.3 based on the dichotomous outcome for throat pain. The ROC curve revealed that a VAS score < 1.0 was the best cut-off point for recovery, with a sensitivity of 0.74 and a specificity of 0.90. CONCLUSION: Almost all the patients had recovered by day 8. A high correlation was found between sickness and sore throat. These data will assist clinicians and others promoting self-care to set realistic expectations regarding recovery from URTI in young adults.
机译：目的：评估可疑病毒性咽喉炎的自然临床过程。设计：前瞻性队列研究。地点：挪威的五个军营。方法：在一项随机安慰剂对照试验中，比较了牛初乳片或安慰剂对青壮年非链球菌性咽喉炎的影响，未发现病程长短有统计学差异。因此，参与者被视为一个队列。作者使用1.0 cm作为恢复的临界值，分析了10.0 cm的“疾病”和喉咙痛的视觉模拟量表（VAS）得分。他们还探索了用于喉咙痛的VAS是否是通过使用接收器工作特性（ROC）曲线来区分是否恢复的良好测试。结果：对于喉咙痛，发现到第6天已恢复了51％，到第8天已恢复了91％。同样，对于疾病，到第6天已恢复了65％，到第8天已恢复了94％。疾病和喉咙痛高度相关（p 0.001）。从“疾病”和喉咙痛（基于VAS评分）恢复的主题日，分别为5.5和4.7，基于喉咙痛的二分结果为5.3。 ROC曲线显示，VAS评分<1.0是恢复的最佳临界点，灵敏度为0.74，特异性为0.90。结论：几乎所有患者在第8天就已康复。疾病与喉咙痛之间存在高度相关性。这些数据将帮助临床医生和其他促进自我保健的人设定有关年轻人从URTI康复的现实期望。

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