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Studies based on the Danish Multiple Sclerosis Registry

机译:基于丹麦多发性硬化症注册表的研究

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Introduction: This paper reviews the most important articles using data from the Danish Multiple Sclerosis Registry (DMSR) published in the past 25 years. Research topics: These articles include: descriptive epidemiological studies, indicating that the female incidence of multiple sclerosis (MS) in Denmark has increased considerably; follow-up studies on social events, showing that patients at a high rate lose their working ability and their spouses/partners; mortality studies, demonstrating a considerable excess mortality; cause-of-death studies; comorbidity studies; and, most importantly, historical prospective studies identifying some risk factors (e.g. infectious mononucleosis) and refuting others (head trauma and a number of occupational exposures e.g. nurses, utility workers, people exposed to solvents). The most important results are briefly presented. Conclusion: The Danish MS register has proven to be a valuable tool for MS epidemiology and has provided knowledge that could not otherwise be achieved.
机译:简介:本文使用过去25年中发布的丹麦多发性硬化症注册中心(DMSR)的数据回顾了最重要的文章。研究主题:这些文章包括:描述性流行病学研究,表明丹麦多发性硬化症(MS)的女性发病率显着增加;有关社会事件的后续研究,表明患者大量丧失工作能力和配偶/伴侣;死亡率研究,证明相当高的死亡率;死因研究;合并症研究;最重要的是,历史前瞻性研究确定了一些危险因素(例如传染性单核细胞增多症),并驳斥了其他危险因素(头部外伤和许多职业暴露,例如护士,公用事业工人,接触溶剂的人)。简要介绍了最重要的结果。结论:丹麦MS登记册已被证明是MS流行病学的宝贵工具,并且提供了否则无法获得的知识。

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