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首页> 外文期刊>Scandinavian journal of clinical and laboratory investigation. >Lower hemoglobin with lower ferritin - results from the HUNT 2 Study
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Lower hemoglobin with lower ferritin - results from the HUNT 2 Study

机译：较低的血红蛋白和较低的铁蛋白-HUNT 2研究的结果

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Aim. We wanted to study the association between blood hemoglobin concentration (b-hemoglobin) and serum ferritin concentration (s-ferritin) in a healthy female population, and compare the findings to those in a previous study of ambulant female patients. Methods. We compared median b-hemoglobin and the fraction with anemia in groups of women with s-ferritin from less than 10 mu g/L to 100 mu g/L. These women, aged 20-55 years, were part of a health screening survey (HUNT 2) where they reported to have 'good' or 'very good' general health and were found to have normal s-creatinine. The s-ferritin values were adjusted to the level of the previous study. The 10, 50 and 90 percentiles of b-hemoglobin were modelled as functions of s-ferritin using quantile regression. Results. Among 2122 healthy females the entire b-hemoglobin distribution was shifted downwards in women with s-ferritin less than 20 mu g/L. Accordingly, the median b-hemoglobin was statistically significantly lower. In women with s-ferritin less than 20 mu g/L the fraction with anemia was 0.15. Conclusions. Lower s-ferritin is associated with lower b-hemoglobin in many more subjects than those labelled anemic.
机译：目标。我们想研究健康女性人群中血红蛋白浓度（b-血红蛋白）与血清铁蛋白浓度（s-铁蛋白）之间的关系，并将其与以前的流动女性患者研究进行比较。方法。我们比较了β-铁蛋白的中位b-血红蛋白水平和贫血分数，其中s-铁蛋白的妇女从低于10μg/ L至100μg/ L。这些女性年龄在20-55岁之间，是健康检查调查（HUNT 2）的一部分，据报告，她们的总体健康状况“良好”或“非常好”，并被发现正常的s-肌酐。将s-铁蛋白值调节至先前研究的水平。使用分位数回归将10％，50％和90％的b-血红蛋白建模为s-铁蛋白的功能。结果。在2122名健康女性中，S-铁蛋白低于20μg / L的女性的整体b-血红蛋白分布向下移动。因此，中值b-血红蛋白在统计学上显着降低。 S-铁蛋白低于20μg / L的女性贫血比例为0.15。结论在比标记为贫血的受试者多得多的受试者中，较低的s-铁蛋白与较低的b-血红蛋白相关。

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