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首页> 外文期刊>Seminars in cutaneous medicine and surgery. >Potential complications of segmental hemangiomas of infancy.
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Potential complications of segmental hemangiomas of infancy.

机译：婴儿节段性血管瘤的潜在并发症。

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Although the majority of hemangiomas of infancy can be expected to follow a benign course, a significant subset may result in serious complications. Recently, hemangiomas of segmental morphology, or those which are large, plaque-like, and patterned in distribution, have been recognized as important markers for potential complications. PHACE syndrome represents the best known example of the variety of problems that can occur in this setting. The PHACE acronym, which stands for posterior fossa brain malformations, segmental cervicofacial hemangiomas, arterial anomalies, cardiac defects and coarctation of the aorta, and eye anomalies, is sometimes referred to as PHACE(S) when ventral developmental defects such as sternal clefting and supraumbilical raphe are present. This article reviews the specific manifestations of PHACE, reflects on pathogenesis, and discusses appropriate work-up and future directions for this complex and fascinating syndrome. We also discuss other complications associated with hemangiomas of segmental morphology, including ulceration, potential visceral involvement, and underlying anomalies related to the lumbosacral location.
机译：尽管可以预期大多数婴儿血管瘤会遵循良性病程，但是很大一部分可能会导致严重的并发症。近来，节段性血管瘤或大的，斑块状且分布规律的血管瘤已被认为是潜在并发症的重要标志。 PHACE综合征是这种情况下可能发生的各种问题的最著名例子。 PHACE的首字母缩写，代表后颅窝畸形，节段性颈面部血管瘤，动脉异常，心脏缺陷和主动脉缩窄以及眼部异常，当腹侧发育缺陷（如胸骨ternal裂和脐上裂）时，有时被称为PHACE（S）缝制存在。本文回顾了PHACE的具体表现，对发病机理进行了反思，并讨论了该复杂而引人入胜的综合症的适当治疗方法和未来方向。我们还讨论了与节段性血管瘤相关的其他并发症，包括溃疡，潜在的内脏受累以及与腰s部位置有关的潜在异常。

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